"The determination of the LPA level in ovarian cancer patients"@en . . . "Zaveden\u00ED metodiky stanoven\u00ED hladiny LPA a jej\u00ED specifikace v plazm\u011B pomoc\u00ED vysoko\u00FA\u010Dinn\u00E9 kapil\u00E1rn\u00ED elektrofor\u00E9zy s nep\u0159\u00EDmou UV detekc\u00ED. Zhodnocen\u00ED rozd\u00EDlu hladin LPA v plazm\u011B zdrav\u00FDch \u017Een a pacientek s ovari\u00E1ln\u00EDm karcinomem. Ve skupin\u011B p\u0159ibli\u017En\u011B 100 pacientek s ovari\u00E1ln\u00EDm karcinomem vyhodnocen\u00ED hladiny LPA v plazm\u011B v z\u00E1vislosti na st\u00E1diu, histologick\u00E9m typu n\u00E1doru, typu chemoterapie, pop\u0159. rekurenci onemocn\u011Bn\u00ED. Stanoven\u00ED hladiny LPA ve vzorku ovari\u00E1ln\u00ED tk\u00E1n\u011B zm\u011Bn\u011Bn\u00E9 n\u00E1dorov\u00FDm procesem u \u010D\u00E1sti pacientek a zhodnocen\u00ED jej\u00EDho v\u00FDznamu. V z\u00E1v\u011Bru studie stanoven\u00ED rozhodovac\u00EDho limitu hladiny LPA v dan\u00E9 skupin\u011B pacientek s ovari\u00E1ln\u00EDm karcinomem." . . . "lysophosphatidic acid;ovarian cancer;plasma;tumor marker;electrophoresis"@en . "Stanoven\u00ED hladiny LPA u pacientek s ovari\u00E1ln\u00EDm karcinomem" . . . . . "http://www.isvav.cz/projectDetail.do?rowId=NH7666"^^ . "2006-06-23+02:00"^^ . . "plasma" . "0"^^ . "Patients with ovarian cancer had statistically significant higher lysophosphatidic acid plasma level (all sutypes) compared with the healthy control group without ovarian pathology.LPA evaluation and its specification improve ovarian cancer diagnostic."@en . . . . "ovarian cancer" . . "An implementation of methodics for the determination of the LPA level and its specification in a plasma of ovarian cancer patients by capillary electrophoresis using indirect UV detection. Rating of differentation of LPA plasma levels in healthy women and in ovarian cancer patients. LPA plasma level rating in a sample of about 100 ovarian cancer patients in dependence on the stage, the histological tumor type, the chemotherapy and the disease rekurrence. The determination of the LPA level in an ovarian tissue sample changed by tumor process at a part of patients and valuation its importance. In the end of this study a cutoff value for the LPA level in ovarian cancer patients will be determined."@en . "lysophosphatidic acid" . "NH7666" . . "4"^^ . "0"^^ . . "4"^^ . "tumor marker" . . "Prok\u00E1zali jsme statist. v\u00FDznamn\u011B vy\u0161\u0161\u00ED hodnoty sumy LPA a jednotl. podtyp\u016F lysofosfatidov\u00E9 kyseliny u pacientek s karcinomem ovaria v porovn\u00E1n\u00ED s \u017Eenami zdrav\u00FDmi.Stanoven\u00ED LPA a jej\u00ED specifikace v plazm\u011B zefektivn\u00ED diagnostiku ovari\u00E1ln\u00EDho karcinomu."@cs . "1"^^ . . . .