"Lipoperoxidation" . "16"^^ . . . . "16"^^ . . . . "Prospective clinical study of the mutual interactions and particular role of fundamental lipid related mechanisms in all-cause morbidity and mortality of nonagenarians. Project will investigate changes and correlation of the: i) plasma and cell membrane unsaturated fatty acids, ii) lipoperoxidation processes and antioxidant consumption, iii) cholesterol biosynthetic pathway and its intermediary products. Conclusions will be made to identify biochemical markers of chronic illnesse and disability. The results might improve our knowledge and thus treatment of degenerative disease in the elderly, being the leading cause of morbidity and mortality in Czech Republic."@en . . "NG6770" . "http://www.isvav.cz/projectDetail.do?rowId=NG6770"^^ . "2004-07-12+02:00"^^ . "Prospektivn\u00ED klinick\u00E1 studie vz\u00E1jemn\u00E9 intekakce a \u00FAlohy nejd\u016Fle\u017Eit\u011Bj\u0161\u00EDch lipidov\u00FDch mechanism\u016F v souvislosti s p\u0159\u00ED\u010Dinami morbidity a mortality u dlouhov\u011Bk\u00FDch pacient\u016F. Projekt bude zkoumat zm\u011Bny a korelace: i) polynenasycen\u00E9 mastn\u00E9 kyseliny v plazm\u011B a bun\u011B\u010Dn\u00E9 membr\u00E1n\u011B, ii) pr\u016Fb\u011Bh lipoperoxidace a konsumpce antioxidant\u016F. iii) synt\u00E9za cholesterolu a jeho intermedi\u00E1rn\u00EDch produkt\u016F. Z\u00EDskan\u00E9 v\u00FDsledky by m\u011Bly p\u0159isp\u011Bt k pozn\u00E1n\u00ED biochemick\u00FDch marker\u016F chronick\u00FDch chorob, morbidity a mortality. Nov\u00E9 poznatky by m\u011Bly prohloubit na\u0161e znalosti a tak\u00E9 l\u00E9\u010Dbu degenerativn\u00EDch onemocn\u011Bn\u00ED, kter\u00E1 jsou nej\u010Dast\u011Bj\u0161\u00EDmi p\u0159\u00ED\u010Dinami morbidity a mortality u gerontologick\u00E9 populace v \u010Cesk\u00E9 republice." . "0"^^ . "Aging;Atherosclerosis;Hyperlipidemia;Cholesterolsynthesis;Fatty acids;Lipoperoxidation;Vitamin E"@en . "Nov\u00E9 poznatky o lipidech u star\u00E9 populace."@cs . . . "0"^^ . . "Cholesterolsynthesis" . "Hyperlipidemia" . "1"^^ . "The importance of lipid metabolism monitoring in aging"@en . . "V\u00FDznam monitorov\u00E1n\u00ED metabolismu lipid\u016F v procesu st\u00E1rnut\u00ED" . . . "Atherosclerosis" . . "Aging" . "Fatty acids" . . .