. . "2005-07-18+02:00"^^ . "Authors will study cardiovascular risk factors in the subjects over 70 years in parallel with the centres in France. It is a two-year prospective study called PROTEGER. The main result will be a complex model for prediction of cardiovascular risk and risk of total mortality. Such a model has not yet been validated in the elderly subjects. Besides classical factors, a large number of %22never%22 ones will be studied: the parameters of function and structure of large arteries, echocardiographic and biological parameters."@en . "large arteries" . "Kardiovaskul\u00E1rn\u00ED riziko u nemocn\u00FDch ve v\u011Bku nad 70 let: \u00FAloha neinvazivn\u00EDho vy\u0161et\u0159en\u00ED c\u00E9vn\u00EDho syst\u00E9mu a srdce a biologick\u00FDch faktor\u016F v p\u0159edpov\u00EDd\u00E1n\u00ED nemocnosti a \u00FAmrtnosti" . . "atherosclerosis" . "prospective study" . . "elderly subjects" . "24"^^ . "Auto\u0159i hodlaj\u00ED studovat prediktivn\u00ED faktory kardiovaskul\u00E1rn\u00EDho rizika u nemocn\u00FDch ve v\u011Bku nad 70 let paraleln\u011B s centry ve Francii. Jedn\u00E1 se o prospektivn\u00ED studii s dvoulet\u00FDm sledov\u00E1n\u00EDm. V\u00FDsledkem bude komplexn\u00ED model predikce kardiovaskul\u00E1rn\u00EDho rizika a rizika \u00FAmrt\u00ED ze v\u0161ech p\u0159\u00ED\u010Din, tento model dosud neexistuje u star\u0161\u00EDch nemocn\u00FDch. Budou studov\u00E1ny parametry z\u00EDskan\u00E9 neinvazivn\u00EDm vy\u0161et\u0159en\u00EDm velk\u00FDch c\u00E9v nov\u00FDmi metodami (aplana\u010Dn\u00ED tonometrie, rychlost \u0161\u00ED\u0159en\u00ED pulzov\u00E9 vlny po aort\u011B a dal\u0161\u00ED), parametry z\u00EDskan\u00E9 echokardiograficky a laboratorn\u00EDmi parametry." . . "Posouzen\u00ED fce velk\u00FDch c\u00E9v p\u0159isp\u00EDv\u00E1 k hodnocen\u00ED kardiovaskul\u00E1r. rizik (KVR). Perif. augmenta\u010Dn\u00ED index (PAI) vykazuje nejt\u011Bsn\u011Bj\u0161\u00ED asociaci s KVR v popula\u010Dn\u00EDch studi\u00EDch. Rychlost \u0161\u00ED\u0159en\u00ED pulzov\u00E9 vlny a nikoliv PAI odli\u0161uje star\u0161\u00ED pacienty od zdrav\u00FDch kontrol"@cs . "24"^^ . . "NG6757" . "homocysteine" . . . "cardiovascular risk;elderly subjects;large arteries;atherosclerosis;prospective study;homocysteine;pulse wave analysis"@en . . . . . . "http://www.isvav.cz/projectDetail.do?rowId=NG6757"^^ . "cardiovascular risk" . . . "Cardiovascular risk in the subjects over 70 years: the role of noninvasive examination of vessels and heart and of biological factors in predictiong morbidity and mortality"@en . . . . "0"^^ . . "Evaluation of function of large arteries contributes to assessment of cardiovascular risks. Peripheral augmentation index showed the closest association with CVR in population based study. Pulse wave velocity and not PAI differentiates elderly patients."@en . . "1"^^ . . "1"^^ .