"Byl dokumentov\u00E1n vliv kr\u00E1tkodob\u00E9ho pod\u00E1v\u00E1n\u00ED kortikoid\u016F na limbick\u00E9 struktury mozku."@cs . "MRI" . . . . "hippocampus" . "Prednisone" . "0"^^ . "2004-07-12+02:00"^^ . . . . . . . "http://www.isvav.cz/projectDetail.do?rowId=NF6489"^^ . "Pomoc\u00ED MRI volumetrie, neuropsychologick\u00FDch test\u016F a endokrinologick\u00E9ho vy\u0161et\u0159en\u00ED objasn\u00EDme vztah mezi dlouhodobou l\u00E9\u010Dbou kortikoidy a struktur\u00E1ln\u00EDmi a funk\u010Dn\u00EDmi zm\u011Bnami hipokampu. P\u016Fjde o longitudin\u00E1ln\u00ED sledov\u00E1n\u00ED skupiny 20 pacient\u016F (power - 95%) u nich\u017E se za\u010D\u00EDn\u00E1 s l\u00E9\u010Dbou kortikoidy." . "Can administration of corticosteroids lead to structural changes in hippocampus? Prospective MRI study in human patients treated with high doses of corticosteroids."@en . . "NF6489" . . . . "P\u016Fsob\u00ED exogenn\u011B pod\u00E1van\u00E9 kortikoidy struktur\u00E1ln\u00ED zm\u011Bny hipokampu? Longitudi\u00E1ln\u00ED studie s vyu\u017Eit\u00EDm MRI volumetrie u pacient\u016F u\u017E\u00EDvaj\u00EDc\u00EDch kortikoidy" . "volumetry" . "8"^^ . "corticosteroids" . . "8"^^ . "hippocampus;corticosteroids;Prednisone;MRI;volumetry;atrophy"@en . "Using the MRI volumetry, neuropsychological assessment and endocrinological screening, we will elucidate the relationship between long term treatment with corticosteroids and structural and functional changes of hippocampus. 20 subjects (power -95%) starting the treatment with corticosteroids will be studied by within subject design paradigm."@en . . . "1"^^ . "3"^^ . .