. "Differentiation" . . "Stem cells" . . "NOD/SCID mice" . "Ribosomal protein S19" . "http://www.isvav.cz/projectDetail.do?rowId=NE6689"^^ . . "Inherited disorders of hematopoessis"@en . "Vrozen\u00E9 defekty hematopoesy" . . "Molecular genetic studies of the pathogenesis of Diamond-Blackfan anemia (DBA). Genetic analysis of candidate genes for DBA/ the role of haploinsuficiency of ribosomal protein S19 (RPS) in human hematopoiesis Murine model of the human hematopoiesis of DBA patients/ the role of modulatory cytokines on DBA hematopoiesis engrafted in NOD/SCID mice. Mechanismus of pathogenesis of primary familial and congenital polycythemia (PFCP)/ genetic analyses of candidate genes for PFCP, novel diagnostic approaches."@en . "17"^^ . "Erythropoietin" . "17"^^ . "Diamond Blackfan anemia;Primary polycythemia;Erythropoietin;Ribosomal protein S19;NOD/SCID mice;Stem cells;Differentiation;Mutation"@en . "0"^^ . "Diamond Blackfan anemia" . "NE6689" . . . "2004-07-12+02:00"^^ . . "1"^^ . "P\u0159\u00EDnosem projektu je dal\u0161\u00ED pozn\u00E1n\u00ED patogeneze DBA."@cs . . "1"^^ . . . . . "Studium mechanism\u016F patogeneze Diamond-Blackfanovy anemie (DBA). Genetick\u00E1 anal\u00FDza kandid\u00E1tn\u00EDch gen\u016F proDBA/ studium vlivu haploinsuficience RPS19 na lidskou hematopoezu. My\u0161\u00ED model na lidsk\u00E9 hematopoezy pacient\u016F s DBA/vliv r\u016Fstov\u00FDch faktor\u016F na hematopoetick\u00E9 bu\u0148ky na modelu NOD/SCID in vivo. Studium mechanism\u016F patogeneze prim\u00E1rn\u00ED famili\u00E1ln\u00ED a kongenit\u00E1ln\u00ED polycytemie (PFCP)/ genetick\u00E1 anal\u00FDza a nov\u00E9 diagnostick\u00E9 metody." . . "Primary polycythemia" . . .