. "0"^^ . . "rRNA" . . "0"^^ . . "1"^^ . . "Proliferation" . . "Ribosomal gene" . "Phosphorylation" . "Investigation of the fuctional link between expression and phosphorylation of nucleolar transcription factors and regulatory mechanism of ribosomal RNA synthesis performed on normal and leukemic blood cells with stimulated or respressed growth activity."@en . . "Study of the regulation of ribosomal RNA synthesis in normal and malignant blood cells."@en . . . "7"^^ . . "7"^^ . "Nucleolus;Ribosomal gene;rRNA;UBF;SL1;Phosphorylation;Proliferation;Leukemia"@en . "SL1" . "V \u010Dasn\u00E9 etap\u011B transformace doch\u00E1z\u00ED k uvol\u0148ov\u00E1n\u00ED t\u011Bsn\u00E9ho chromatinov\u00E9ho uspo\u0159\u00E1d\u00E1n\u00ED oblast\u00ED rDNA, ve kter\u00FDch je v\u00E1z\u00E1n UBF (transkrip\u010Dn\u00ED faktor), kter\u00FD pak podl\u00E9h\u00E1 fosforylaci a participuje na aktivn\u00ED tvorb\u011B robozon\u00E1ln\u00EDch prekurzor\u016F.V pozd\u011Bj\u0161\u00ED etap\u011B transf."@cs . "Studium regulace synt\u00E9zy ribozom\u00E1ln\u00ED RNA v norm\u00E1ln\u00EDch a malign\u00EDch krevn\u00EDch bu\u0148k\u00E1ch." . "Nucleolus" . "NC5933" . "Studium funk\u010Dn\u00EDho spojen\u00ED mezi expres\u00ED a reverzibiln\u00ED fosforylac\u00ED nukleol\u00E1r.protein. faktor\u016F a regulac\u00ED synt\u00E9zy ribozom\u00E1ln\u00ED RNA prov\u00E1d\u011Bn\u00E9 na bun\u011B\u010Dn\u00FDch modelech reprezent. norm\u00E1l.a leukem. hematopoetic.i bu\u0148kami indukovat.i k aktivaci \u010Di represi prolifer." . . "UBF" . . . . "http://www.isvav.cz/projectDetail.do?rowId=NC5933"^^ . . "2003-07-31+02:00"^^ . .