. "male rats" . "2006-06-23+02:00"^^ . "Osteoporotic changes in bone are characterized by changes in both density and structure. Little is known about the effects of estrogen on bone metabolism and bone strength in men. Orchidectomy is the most popular model for studying the events associated with the lack of testosterone. Not only androgens however but also estrogens may be important for the growth and maintenance of the male skeleton. In our experiments we want to use bending tests, biochemical markers of bone turnover and bone density to asses biomechanical properties of bones from orchiectomized rats and rats treated with different doses of estrogens."@en . . . "Effects of estrogen status on mechanical properties and biochemical markers of bone turnover in male rats."@en . "Vliv estrogen\u016F na mechanick\u00E9 vlastnosti a biochemick\u00E9 ukazatele kostn\u00EDho obratlu u potkan\u00EDch samc\u016F." . . . "orchidectomy" . . "We tested effect of alendronate administration on bone mineral density and bone strength in castrated rats.We proved the effect of chronic nicotine and alcohol administration on bone mineral content and bone strength in male rats."@en . . "Prok\u00E1zali jsme, \u017Ee nejroz\u0161\u00ED\u0159. l\u00E9k na osteopor\u00F3zu alendronat,kter\u00FD zvy\u0161uje kostn\u00ED densitu,nepo\u0161kozuje mechanickou pevnost kosti.Chronick\u00E9 pod\u00E1v\u00E1n\u00ED nikotinu nebo alkoholu vede k po\u0161kozen\u00ED kost.mechan.,sni\u017Euje pevnost kosti."@cs . "Mechanical properties" . . . "osteoporosis;orchidectomy;bending test;Mechanical properties;estrogen;male rats;Bone metabolism"@en . . . "7"^^ . "7"^^ . . . "estrogen" . . "Osteopor\u00F3za u mu\u017E\u016F je vzr\u016Fstaj\u00EDc\u00ED zdravotn\u00ED probl\u00E9m s dosud nedo\u0159e\u0161enou atiopatogenez\u00ED. Vedle \u00FA\u010Dinku testosteronu na kost se uplat\u0148uj\u00ED velice pravd\u011Bpodobn\u011B i estrogeny. Vedle kostn\u00ED density, tj. obsahu miner\u00E1l\u016F v kosti, kterou m\u011B\u0159\u00EDme densitometrem, st\u00E1le v\u00EDce se mluv\u00ED o mechanick\u00FDch vlastnostech kosti, kter\u00E9 zat\u00EDm u lid\u00ED m\u011B\u0159it neum\u00EDme. Ty budeme zji\u0161\u0165ovat pomoc\u00ED t\u0159\u00EDbodov\u00E9ho ohybu kost\u00ED z vykastrovan\u00E9ho samce. Chceme zjistit \u00FA\u010Dinek r\u016Fzn\u00FDch d\u00E1vek estrogen\u016F na densitu, biochemick\u00E9 markery kostn\u00EDho obratu a mech. odolnost kosti." . "NB7508" . . "osteoporosis" . . . "0"^^ . . "bending test" . . "1"^^ . "1"^^ . "http://www.isvav.cz/projectDetail.do?rowId=NB7508"^^ .