"ateroskler\u00F3za" . "V prospektivn\u00ED klinick\u00E9 studii u souboru 159 pacient\u016F s famili\u00E1rn\u00ED hypercholesterol\u00E9mi\u00ED vy\u0161et\u0159en\u00FDch koronarograficky byl sledov\u00E1n stupe\u0148 z\u00E1va\u017Enosti sten\u00F3zy a zji\u0161t\u011Bny vztahy ke slo\u017Een\u00ED mastn\u00FDch kyselin a koncentrac\u00EDm lipoperoxida\u010Dn\u00EDch produkt\u016F."@cs . "ICHS" . "apo E;ateroskler\u00F3za;FH;ICHS;LDL receptor;lipoperoxidace;PUFA;vitamin E"@en . . . "http://www.isvav.cz/projectDetail.do?rowId=NB5205"^^ . . "2004-03-23+01:00"^^ . "Prospective clinical study of the mutual interactions and particular role of phenotype and genotype of hyperlipoprot. in atherogenesis of coronary heart disease patients to investigate correlation of occurrence and the grade of coron. atherosclerosis 1. plasma and cell membrane structure of unsaturated and saturated fatty acids, 2. lipoperoxidation formation and antioxidant consuption, 3. apoprotein E genotype, 4. LDL - receptor genotype, 5. LDL - receptor activity."@en . "PUFA" . . . "6"^^ . "LDL receptor" . . "6"^^ . . . . . . "1"^^ . "The role of phenotype and genotype of familial hyperlipoproteinaemia in atherogenesis of coronary artery disease."@en . "FH" . "\u00DAloha fenotypu a genotypu famili\u00E1rn\u00ED hyperlipoprotein\u00E9mie v procesu aterogeneze u ischemick\u00E9 choroby srde\u010Dn\u00ED." . . "Prospektivn\u00ED klinick\u00E1 studie vz\u00E1jemn\u00E9 vazby a \u00FAlohy fenotypu a genotypu hyperlipoprotein\u00E9mi\u00ED v procesu aterogeneze u pacient\u016F s ischemickou chorobou srde\u010Dn\u00ED, s c\u00EDlem posoudit korelaci v\u00FDskytu a z\u00E1va\u017Enosti event. koron\u00E1rn\u00ED ateroskletosy s : i) plasmatick\u00FDm a membr\u00E1nov\u00FDm slo\u017Een\u00EDm nenasycen\u00FDch a nasycen\u00FDch mastn\u00FDch kyselin, ii) antioxida\u010Dn\u00EDm profilem, iii) genotypem apoproteinu E, iv) genotypem LDL - receptor\u016F, v) funk\u010Dn\u00ED aktivitou LDL - receptor\u016F." . "0"^^ . . . "lipoperoxidace" . "NB5205" . . "0"^^ . "apo E" .