"myocardium; ischemic heart disease; adaptation; cardioprotection"@en . "2010-06-30+02:00"^^ . . "MEB080837" . "2"^^ . "0"^^ . . . "2008-01-01+01:00"^^ . "2"^^ . "1"^^ . "Z\u00EDskan\u00E9 poznatky by m\u011Bly p\u0159isp\u011Bt k hlub\u0161\u00EDmu pozn\u00E1n\u00ED patogeneze ischemick\u00E9ho po\u0161kozen\u00ED myokardu, kter\u00E9 je p\u0159edpokladem pro v\u00FDvoj nov\u00FDch p\u0159\u00EDstup\u016F k ochran\u011B p\u0159ed ischemi\u00ED, perspektivn\u011B vyu\u017Eiteln\u00FDch p\u0159i prevenci a l\u00E9\u010Db\u011B tohoto z\u00E1va\u017En\u00E9ho onemocn\u011Bn\u00ED." . . "myocardium" . . . "2009-03-09+01:00"^^ . "http://www.isvav.cz/projectDetail.do?rowId=MEB080837"^^ . " ischemic heart disease" . "2009-12-31+01:00"^^ . . " adaptation" . . "0"^^ . . . . . . "Results should contribute to better understanding the pathogenesis of myocardial ischemic injury as a prerequisite for the development of new approaches to the prevention and treatment of ischemic heart disease."@en . "Hlavn\u00EDm v\u00FDsledkem bylo zji\u0161t\u011Bn\u00ED, \u017Ee aktivace PI3K/Akt hraje \u00FAlohu v mechanismu omezen\u00ED infarktu myokardu ischemick\u00FDm \u010Di farmakologick\u00FDm preconditioningem, neuplat\u0148uje se v\u0161ak v antiarytmnick\u00E9m \u00FA\u010Dinku. V\u00FDsledky byly publikov\u00E1ny ve 3 \u010Dl\u00E1nc\u00EDch a prezentov\u00E1ny na \u0159ad\u011B konferenc\u00ED."@cs . . "Aktivace bun\u011B\u010Dn\u00FDch adapta\u010Dn\u00EDch mechanism\u016F jako mo\u017En\u00FD p\u0159\u00EDstup k ochran\u011B srdce p\u0159ed ischemick\u00FDm po\u0161kozen\u00EDm" . "It was found that activation of PI3K/Akt cadcade is invelved in the infarct size-limiting mechanism of ischemic and pharmacological preconditioning, but it does not play a role in the antiarrhythmic protection. Results were published in 3 papers and presented at several conferences."@en . . "Activation of cellular adaptive as a potential approach to cardiac protection against ischemic injury"@en . . .