" antitumor drugs" . . . . "Spole\u010Dn\u00E9 a komplement\u00E1rn\u00ED studie s partnersk\u00FDm pracovi\u0161t\u011Bm v \u010C\u00EDn\u011B poskytly v\u00FDsledky, kter\u00E9 ukazuj\u00ED na mo\u017Enosti vyu\u017Eit\u00ED nov\u00FDch komplex\u016F p\u0159echodn\u00FDch kov\u016F jako nov\u00E1, \u00FA\u010Dinn\u011Bj\u0161\u00ED agens vhodn\u00E1 pro chemoterapii n\u00E1dor\u016F. \u0158e\u0161en\u00ED projektu umo\u017Enilo pod\u00EDlet se na aktivit\u00E1ch mezin\u00E1rodn\u00ED spolupr\u00E1ce ve v\u00FDzkumu a v\u00FDvoji, zalo\u017Een\u00FDch na mezin\u00E1rodn\u00ED smlouv\u011B o v\u011Bdeckotechnick\u00E9 spolupr\u00E1ci mezi \u010CR a \u010C\u00EDnou."@cs . "2012-02-16+01:00"^^ . . . " DNA" . " chemotherapy" . "1"^^ . "http://www.isvav.cz/projectDetail.do?rowId=ME10066"^^ . . "The main objective is to increase knowledge and understanding of the mechanisms of action of antitumour metallodrugs, and to use this enhanced knowledge in combination with modern genomic research to develop new classes of metallodrugs with truly novel mechanisms of action and novel spectra of biomedical activity."@en . "0"^^ . . . "0"^^ . . . "Transition metal-based anticancer compounds. From mechanistic studies to innovatory cancer chemotherapy"@en . "ME10066" . . "C\u00EDlem tohoto v\u00FDzkumu je zjistit \u00FAdaje o molekul\u00E1rn\u00EDch mechanismech protin\u00E1dorov\u00E9ho p\u016Fsoben\u00ED metalofarmak odvozen\u00FDch od p\u0159echodn\u00FDch kov\u016F. Nov\u00E9 znalosti z\u00EDskan\u00E9 p\u0159i \u0159e\u0161en\u00ED tohoto projektu vyu\u017E\u00EDt pro n\u00E1vrhy nov\u00FDch typ\u016F cytostatik" . . . "2010-05-01+02:00"^^ . " ruthenium" . "Cancer" . . . . "Protin\u00E1dorov\u011B \u00FA\u010Dinn\u00E9 slou\u010Deniny p\u0159echodn\u00FDch kov\u016F. Od mechanistick\u00FDch studi\u00ED k inovac\u00EDm v chemoterapii rakoviny" . . "9"^^ . . . "9"^^ . "Joint and complementary studies with researchers in China yielded results showing that new metal based complexes can be used as new, more efficient antitumor drugs. The implementation of this project made it possible to participate in the international cooperation in R&D based on the agreement on the scientific and technical cooperation between Czech Republic and China."@en . "Cancer; chemotherapy; antitumor drugs; DNA; platinum; ruthenium; antitumor activity"@en . " platinum" . . "2013-06-28+02:00"^^ . "2012-12-31+01:00"^^ .