"The aim of this study is to evaluate the effect of catheter ablation of VT after myocardial infarction and compare catheter ablation with magnetic navigation and manual navigation. Included 63 pts. Complete elimination of VT in 56 pts. Recurrence of VT 9,5 %, long lasting effect of ablation 90,5 %. Magnetic navigation (31 pts) shows decrease in fluoroscopy time (5,2 minutes vs. 24,6 minutes)."@en . "2010-12-31+01:00"^^ . . . . . . " ventricular tachycardia" . . " ventricular fibrillation" . . . "0"^^ . . . "C\u00EDlem t\u00E9to klinick\u00E9 studie je zjistit, zda katetriza\u010Dn\u00ED ablace u nemocn\u00FDch po prod\u011Blan\u00E9m infarktu myokardu s implantovan\u00FDm ICD m\u016F\u017Ee b\u00FDt prov\u00E1d\u011Bna bezpe\u010Dn\u011B; z\u00E1rove\u0148 bude v\u00FDznamn\u011B redukovat po\u010Det vydan\u00FDch ICD p\u0159\u00EDstrojem. Je to prospektivn\u00ED, multicentrick\u00E1, randomizovan\u00E1 studie (1:1) srovn\u00E1vaj\u00EDc\u00ED dva terapeutick\u00E9 p\u0159\u00EDstupy. Nemocn\u00FDm v testovan\u00E9 skupin\u011B bude implantov\u00E1n ICD podle protokolu studie a sou\u010Dasn\u00FDch doporu\u010Den\u00ED. Druh\u00E1 skupina nemocn\u00FDch podstoup\u00ED elektroanatomick\u00E9 mapov\u00E1n\u00ED, aby bylo mo\u017En\u00E9 zn\u00E1zornit endokardi\u00E1ln\u00ED pr\u016Fb\u011Bh hrani\u010Dn\u00EDch z\u00F3n infarktov\u00E9ho lo\u017Eiska. Abla\u010Dn\u00ED modifikace arytmogenn\u00EDho substr\u00E1tu bude prov\u00E1d\u011Bna s vyu\u017Eit\u00EDm strategi\u00ED substr\u00E1tov\u00E9ho mapov\u00E1n\u00ED (tj.c\u00EDlen\u00E9 mapov\u00E1n\u00ED exitov\u00FDch m\u00EDst dokumentovan\u00FDch KT, mapov\u00E1n\u00ED pozdn\u00EDch a fragmentovan\u00FDch potenci\u00E1l\u016F v oblasti infarktov\u00E9 jizvy, atd.). K mapov\u00E1n\u00ED a katetriza\u010Dn\u00ED ablaci budeme vyu\u017E\u00EDvat katetr s otev\u0159en\u00FDm proplachem fyziologick\u00E9ho roztoku s vyu\u017Eit\u00EDm radiofrekven\u010Dn\u00ED energie (NaviStar TM Thermocool catheter , Bionese Webster, Inc.)." . "ME 900" . "1"^^ . "Catheter ablation" . "Substrate modification to prevent ventikular tachyarrhythmias"@en . . . . "Substr\u00E1tov\u00E9 mapov\u00E1n\u00ED jako prevence vzniku komorov\u00FDch tachyarytmi\u00ED" . "0"^^ . . "2007-05-01+02:00"^^ . "6"^^ . . . "Catheter ablation; ventricular tachycardia; ventricular fibrillation; substrate mapping; implantable defibrillator; sudden cardiac death"@en . "6"^^ . "The objective of this clinical investigation is to investigate whether catheter ablation treatment can be used safely and effectively in post-MI patients with an indication for ICD implantation to reduce the number of future ICD therapies. This study is a prospective, multi-center, unblinded, randomized (1:1) clinical trial which will compare two treatment strategies. Subjects will be randomized to either an ICD control group or an ICD + catheter ablation study group. Subjects in both arms will receive an ICD for either primary or secondary prevention of post-MI sudden cardiac death due to ventricular tachycardia or fibrillation (VT/VF) based on established guidelines. Additionally, the study group will undergo a strategy of catheter-based VT substrate modification. Stratification will be performed based on ICD implant for either primary or secondary prevention. Follow-up will be conducted in regular intervals over a 24month period."@en . "2010-02-16+01:00"^^ . . . " implantable defibrillator" . " substrate mapping" . "2011-06-30+02:00"^^ . "http://www.isvav.cz/projectDetail.do?rowId=ME 900"^^ . "Posuzovali jsme, zda katetriza\u010Dn\u00ED ablace KT po prod\u011Blan\u00E9m IM sn\u00ED\u017E\u00ED po\u010Det terapi\u00ED ICD a srovn\u00E1vali jsme magneticky navigovan\u00FD abla\u010Dn\u00ED v\u00FDkon s manu\u00E1ln\u00EDm. Za\u0159azeno 63 pt. Kompletn\u00ED eliminace KT u 56 pt. Recidiva KT u 9,5%, p\u0159\u00EDzniv\u00FD efekt ablace p\u0159etrval u 90,5%. U 31 pt. s magnetickou navigac\u00ED prokazujeme v\u00FDznamn\u00E9 sn\u00ED\u017Een\u00ED RTG z\u00E1\u0159en\u00ED (\u00D8 5,2 min) oproti b\u011B\u017En\u00E9mu v\u00FDkonu (\u00D8 24,6 min)."@cs .