"Project enabled involvement of the laboratory in the program of European Cooperation in Science and Technology (COST) SYSGENET, focused on complex gene interactions using as a model mouse reference populations. The Prague laboratory contributed with a panel of chromosome substitution strains."@en . "Model organisms for himan diseases. Genetic reference populations. Chromosome substitution strains. Genetics of gene expression. Genetics of male sterility."@en . "1"^^ . . "Projekt umo\u017Enil participaci laborato\u0159e v\u00A0programu European Cooperation in Science and Technology (COST) SYSGENET, zam\u011B\u0159en\u00E9m na komplexn\u00ED genov\u00E9 interakce na modelu my\u0161\u00EDch referen\u010Dn\u00EDch populac\u00ED. Pra\u017Esk\u00E1 laborato\u0159 p\u0159isp\u011Bla panelem chromozom\u00E1ln\u00EDch"@cs . . . . . "http://www.isvav.cz/projectDetail.do?rowId=LD11079"^^ . . . . . "0"^^ . . "2014-06-30+02:00"^^ . "New Mouse Models for Studies on Biomedical Complex Traits and Human Diseases and for Systems Genetics"@en . . . "LD11079" . "2013-02-22+01:00"^^ . . . "Nov\u00E9 my\u0161\u00ED modely pro studium biomedic\u00EDnsk\u00FDch komplexn\u00EDch znak\u016F a lidsk\u00FDch chorob a pro syst\u00E9movou genetiku" . . "C\u00EDlem projektu je vyu\u017Eit\u00ED souboru chromozom\u00E1ln\u00EDch substitu\u010Dn\u00EDch kmen\u016F jako modelov\u00FDch organism\u016F pro studium d\u011Bdi\u010Dnosti exprese gen\u016F v r\u016Fzn\u00FDch tk\u00E1n\u00EDch v norm\u00E1ln\u00EDch a pathologick\u00FDch stavech, se zvl\u00E1\u0161tn\u00EDm zam\u011B\u0159en\u00EDm na studium gen\u016F kontroluj\u00EDc\u00EDch sam\u010D\u00ED neplodnost. Tento c\u00EDl pak realizovat ve spolupr\u00E1ci s evropsk\u00FDmi pracovi\u0161ti v r\u00E1mci projektu SYSGENET a zajistit tak jeho integraci v r\u00E1mci evropsk\u00FDch genetick\u00FDch referen\u010Dn\u00EDch populac\u00ED." . . "2013-12-31+01:00"^^ . . "The project is aimed at introduction of intersubspecific chromosome substitution strains as model organanisms for studies of heredity of gene expression levels in various tissues and organs at physiological and pathological states. Special attention is paid to analysis of genes responsible for male sterility. The use of the chromosome substitution strains will be realized in collaboration with the european laboratories ingaged in SYSGENET \u2013 COST project, whose main aim is to integrate genetic resources from individual laboratories into European genetic reference populations (GRP)."@en . . "5"^^ . . "5"^^ . . "0"^^ . "2011-03-01+01:00"^^ .