"http://www.isvav.cz/projectDetail.do?rowId=KJB4050408"^^ . " oncology" . . . "Biocompatible nanosize synthetic polymer-based drug delivery systems (as micells, nanoparticles and soluble polymeric carriers) represent a novel promissing approach how to supress undesired properties and side effects of drugs and selectively aim them to target tissues. These advantages should especially be great in the case of radiopharmaceticals and their targeted delivery. Development and studying properties of selected types of such systems is the aim of the proposed project."@en . "KJB4050408" . "nuclear" . "Biokompatibiln\u00ED drug delivery syst\u00E9my pro nukle\u00E1rn\u00ED medic\u00EDnu" . " iodine" . " drug delivery" . "1"^^ . . . . "2"^^ . " therapy" . . "0"^^ . . "Biocompatible nanosize drug delivery vehicles for nuclear medicine"@en . " cancer" . . "Syst\u00E9my pro dopravu l\u00E9\u010Div nanometrov\u00FDch rozm\u011Br\u016F zalo\u017Een\u00E9 na syntetick\u00FDch polymerech (zejm\u00E9na micely, nano\u010D\u00E1stice a rozpustn\u00E9 polymern\u00ED nosi\u010De) p\u0159edstavuj\u00ED modern\u00ED p\u0159\u00EDstup potla\u010Den\u00ED ne\u017E\u00E1douc\u00EDch vlastnost\u00ED a vedlej\u0161\u00EDch \u00FA\u010Dink\u016F l\u00E9\u010Div a jejich selektivn\u00ED dopravu do c\u00EDlov\u00FDch tk\u00E1n\u00ED. V\u00FDhody t\u011Bchto syst\u00E9m\u016F by m\u011Bly zvl\u00E1\u0161t\u011B vyniknout v p\u0159\u00EDpad\u011B jejich pou\u017Eit\u00ED pro dopravu radiofarmak. V\u00FDvoj a studium vlastnost\u00ED tohoto typu syst\u00E9m\u016F je c\u00EDlem p\u0159edkl\u00E1dan\u00E9ho projektu." . . . " micell" . "V projektu byly studov\u00E1ny pH-sensitivn\u00ED polymern\u00ED micely, st\u0159\u00EDbrn\u00E9 nano\u010D\u00E1stice, vodorozpustn\u00E9 hydroxybisfosfon\u00E1tov\u00FDmi skupinami c\u00EDlen\u00E9 polymery a termoresponsivn\u00ED polymery jako syst\u00E9my pro zv\u00FD\u0161en\u00ED selektivity \u00FA\u010Dinku radiofarmak pro c\u00EDlov\u00E9 tk\u00E1n\u011B."@cs . . " technetium" . " medicine" . "2014-02-12+01:00"^^ . "nuclear; medicine; drug delivery; iodine; astatine; technetium; polymer; therapy; micell; nanoparticle; oncology; cancer; self assembly; biocompatible"@en . . . . "The project concerns pH-sensitive polymeric micelles, silver nanoparticles, water-soluble hydroxybisphosphonate-targeted polymers and thermoresponsive polymers as systems for improving the selectivity of the therapeutic effect of radiopharmaceuticals."@en . . . . " astatine" . . " polymer" . " nanoparticle" . "8"^^ . "8"^^ . . " self assembly" .