" bone cement" . "2005-01-01+01:00"^^ . . . . . . " acetabular implants" . . "Biomechanical Analysis of micromotions and loosening of cemented acetabular"@en . "2009-07-02+02:00"^^ . " abrasion particles of the polyethylene" . "0"^^ . "2008-12-31+01:00"^^ . "2"^^ . . "1"^^ . . . "THR; acetabular implants; bone cement; micromotions; acetabular cup loosening; abrasion particles of the polyethylene; 3-D FE model of the pelvis; CT scans"@en . "Derived method of CT scans of pelvis with creation of the 3D computation model of system pelvis-acetabular cup enables to explain loosening and micromotions of the cemented acetabular cup. The new method LSc was developed for analysis of UHMWPE wear."@en . " micromotions" . . . . "THR" . "IAA200710504" . " 3-D FE model of the pelvis" . "The proposed grant project is of interdisciplinary character and deals with the description of actual biomechanical behaviour of hip joint and the cemented acetabular cups: (i) Construction of 3D FE models of the pelvis with cemented acetabular cups. (ii) Finding of the causes of the development of the micromotions of cemented acetabular cups and analysis of their loosening that can originate during gait loading, because the leaked-out blood creates a mid-layer on the cement-bone interface and the abrasion particles of the polyethylene penetrate into the newly formed interspace and induce formation of osteoagressive granuloma and consecutive osteolysis. Later, the cemented acetabular cup loosening takes place. (ii) Assessment of the microdeformation of the polyethylene cup during the gait loading. (iii) Optimisation of the cement thickness and the diameter, depth and number of acetabular %22keyholes%22 to be drilled into the pelvic bone to maximise the torque rigidity of acetabular cups."@en . "Odvozen\u00E1 metodika CT skenov\u00E1n\u00ED p\u00E1nve s tvorbou 3D v\u00FDpo\u010Dtov\u00E9ho modelu syst\u00E9mu p\u00E1nev-acetabul\u00E1rn\u00ED jamka umo\u017E\u0148uje vysv\u011Btlit uvoln\u011Bn\u00ED a migraci cementovan\u00E9 acetabul\u00E1rn\u00ED jamky. Pro sledov\u00E1n\u00ED ot\u011Bru \u010D\u00E1stic UHMWPE okol\u00ED acetabula byla vypracov\u00E1na metoda LSc."@cs . . "28"^^ . . "28"^^ . . "2008-02-21+01:00"^^ . . . "http://www.isvav.cz/projectDetail.do?rowId=IAA200710504"^^ . "Biomechanick\u00E1 anal\u00FDza mikropohyb\u016F a uvoln\u011Bn\u00ED cementovan\u00FDch acetabul\u00E1rn\u00EDch implant\u00E1t\u016F" . . " acetabular cup loosening" . "Grant je interdisciplin\u00E1rn\u00EDho charakteru a pat\u0159\u00ED do z\u00E1kladn\u00EDho v\u00FDzkumu. Na z\u00E1klad\u011B klinick\u00FDch poznatk\u016F z ortopedie se bude zab\u00FDvat v\u00FDpo\u010Dtov\u00FDm a experiment\u00E1ln\u00EDm modelov\u00E1n\u00EDm biomechanick\u00FDch proces\u016F v ky\u010Deln\u00EDm kloubu, p\u0159\u00ED\u010Din vzniku mikropohyb\u016F cementovan\u00FDch acetabul\u00E1rn\u00EDch implant\u00E1t\u016F a jejich uvol\u0148ov\u00E1n\u00EDm p\u0159i re\u00E1ln\u00E9m zat\u011B\u017Eov\u00E1n\u00ED p\u0159i lidsk\u00E9 aktivit\u011B. Pro anal\u00FDzu budou vytvo\u0159eny kone\u010Dn\u011Bprvkov\u00E9 modely p\u00E1nve s acetabul\u00E1rn\u00ED jamkou na z\u00E1klad\u011B CT sn\u00EDmk\u016F. Bude posouzen vliv ot\u011Brov\u00E9 hmoty z polyetyl\u00E9nu na uvol\u0148ov\u00E1n\u00ED jamky. Bude vypracov\u00E1na metoda pro optimalizaci zp\u016Fsobu ukotven\u00ED cementovan\u00E9 ky\u010Deln\u00ED jamky. D\u00E1le je nutno vytvo\u0159it pomoc\u00ED v\u00FDpo\u010Dtov\u00E9ho modelov\u00E1n\u00ED in\u017Een\u00FDrskou podporu ortop\u00E9d\u016Fm p\u0159i operac\u00EDch na ky\u010Deln\u00EDm kloubu s r\u016Fzn\u00FDm stupn\u011Bm posti\u017Een\u00ED, aby byl dosa\u017Een vysok\u00FD stupe\u0148 poopera\u010Dn\u00ED spolehlivosti. V\u00FDsledkem \u0159e\u0161en\u00ED budou tak\u00E9 krit\u00E9ria po posouzen\u00ED spolehlivosti cementovan\u00E9 acetabul\u00E1rn\u00ED jamky ve srovn\u00E1n\u00ED s necementovanou (mnohem dra\u017E\u0161\u00ED) pro jednotliv\u00E9 operace." . .