. . . " adsorptive transfer technique" . . "IAA1163201" . . "2007-09-26+02:00"^^ . . . . " mercury and solid electrodes" . "Elimination voltammetry with linear scan in combination with adsorptive stripping technique was developed as a perspective tool for the sensitive electroanalytical determ. of homo- and hetero-oligonucleotides, for the estimation of nucleotide sequence"@en . . . . "oligonucleotides" . "Kombinac\u00ED adsorptivn\u00ED rozpou\u0161t\u011Bc\u00ED techniky a elimina\u010Dn\u00ED voltametrie s line\u00E1rn\u00EDm scanem byl vytvo\u0159en perspektivn\u00ED n\u00E1stroj pro citliv\u00E9 analytick\u00E9 stanoven\u00ED homo- i hetero-oligonukleotid\u016F, v\u010Detn\u011B jejich b\u00E1z\u00ED a pro ur\u010Den\u00ED jejich nukleotidov\u00E9 sekvence."@cs . . . . "Nejd\u016Fle\u017Eit\u011Bj\u0161\u00ED c\u00EDle grantov\u00E9ho v\u00FDzkumu jsou (a) vyvinout nov\u00E9 zp\u016Fsoby detekce b\u00E1z\u00ED nukleov\u00FDch kyselin pomoc\u00ED p\u0159enosov\u00E9 techniky ve spojen\u00ED s elimina\u010Dn\u00ED a rozpou\u0161t\u011Bc\u00ED voltametri\u00ED, (b) studovat kr\u00E1tk\u00E9 oligonukleotidy v z\u00E1vislosti na jejich sekvenci a d\u00E9lce a (c) pou\u017E\u00EDt elimina\u010Dn\u00ED voltametrii s line\u00E1rn\u00ED polarizac\u00ED elektrody a elektrochemickou impedan\u010Dn\u00ED spektroskopii v anal\u00FDze oligonukleotid\u016F a nukleov\u00FDch kyselin. Anal\u00FDza bude provedena na rtu\u0165ov\u00FDch a pevn\u00FDch elektrod\u00E1ch. P\u0159edpokl\u00E1d\u00E1 se, \u017Ee v\u00FDsledky z\u00EDskan\u00E9 v tomto grantu budou vyu\u017Eity jako jednoduch\u00E9, citliv\u00E9 a selektivn\u00ED analytick\u00E9 postupy stanoven\u00ED nukleov\u00FDch kyselin a jejich slo\u017Eek. V\u00FDhoda t\u011Bchto analytick\u00FDch postup\u016F spo\u010D\u00EDv\u00E1 v mo\u017Enosti modifikovat elektrody nukleov\u00FDmi kyselinami a oligonukleotidy. Z\u00EDskan\u00E9 v\u00FDsledky najdou uplatn\u011Bn\u00ED v r\u016Fzn\u00FDch oblastech biofyziky, biochemie a molekul\u00E1rn\u00ED biologie." . . "Application of adsorptive transfer and elemination techniques in oligonucleotides and nucleic acids analysis."@en . . "http://www.isvav.cz/projectDetail.do?rowId=IAA1163201"^^ . . "The principal aims of the joint research are (a) to develop new ways of detecting of nucleic acids bases using transfer technique in connection with elimination and stripping voltammetry, (b) to study short oligonucleotides in dependence on their sequence and length and (c) to use elimination voltammetry with linear scan and electrochemical impedance spectroscopy in oligonucleotides and nucleic acids analysis. Analysis will be performed at mercury and solid electrodes. It is expected that the results obtained in this project will be utilized as a simple sensitive and selective analytical procedures for the determination of nucleic acids and their components. The advatage of these analytical procedures consists in the possibility to modify electrodes by nucleic acids and oligonucleotides. Obtained results will be applied in various fields of biophysics, biochemistry and molecular biology."@en . "Vyu\u017Eit\u00ED adsorptivn\u00ED p\u0159enosov\u00E9 a elimina\u010Dn\u00ED techniky pro elektrochemickou anal\u00FDzu oligonukleotid\u016F a nukleov\u00FDch kyselin" . "57"^^ . "57"^^ . . . "0"^^ . . "0"^^ . . "2"^^ . " nucleic acids" . "oligonucleotides; nucleic acids; adsorptive transfer technique; elimination voltammetry nith linear scan; mercury and solid electrodes; biosensors"@en . " elimination voltammetry nith linear scan" .