"Aktivace pam\u011Bti mimo kontext u\u010Den\u00ED - rekonzolidace a z\u00FA\u010Dastn\u011Bn\u00E9 druhy pam\u011Bti" . . . "0"^^ . "GP309/04/P206" . . . . "V\u00FDzkum financovan\u00FD grantem objevil p\u0159\u00EDtomnost rekonzolida\u010Dn\u00ED f\u00E1ze po OCAM a potvrdil tak interpretaci fenom\u00E9nu jako aktivace pam\u011Bti. D\u00E1le prok\u00E1zal nezbytnost proteosynt\u00E9zy pro rekonzolidaci a roli adrenergn\u00EDho syst\u00E9mu v n\u00ED, co\u017E potvrzuje analogii OCAM re"@cs . . "2008-05-19+02:00"^^ . "Research funded by the grant has revealed the presence of a reconsolidation phase following OCAM and has proved our interpretation of the phenomenon as a real memory activation. Further on the work has showed the dependency of memory reactivation upon th"@en . . "1"^^ . . "Navrhovan\u00FD projekt m\u00E1 za c\u00EDl prozkoumat nov\u011B popsan\u00FD fenom\u00E9n aktivace pam\u011B\u0165ov\u00E9 stopy u potkana v situaci kontextu\u00E1ln\u011B v\u00FDrazn\u011B odli\u0161n\u00E9 od t\u00E9, ve kter\u00E9m byla stopa z\u00EDsk\u00E1na. Na\u0161e dosavadn\u00ED experimenty uk\u00E1zaly, \u017Ee b\u011Bhem stresov\u00E9 situace tzv. nucen\u00E9ho plav\u00E1n\u00EDpo dobu 20 minut doch\u00E1z\u00ED k aktivaci jeden den star\u00E9 pam\u011B\u0165ov\u00E9 stopy pro stranovou diskriminaci v Y- bludi\u0161ti. V\u00FDznam uveden\u00E9ho zji\u0161t\u011Bn\u00ED spo\u010D\u00EDv\u00E1 ve skute\u010Dnosti, \u017Ee kontexty obou situac\u00ED jsou z\u00E1sadn\u011B odli\u0161n\u00E9, zat\u00EDmco dosavadn\u00ED n\u00E1zory v oblasti v\u00FDzkumupam\u011Btipova\u017Euj\u00ED za nezbytn\u00E9 pro aktivaci vzpom\u00EDnky alespo\u0148 \u010D\u00E1ste\u010Dnou prezentaci smyslov\u00FDch vjem\u016F vn\u00EDman\u00FDch p\u0159i p\u016Fvodn\u00EDm u\u010Den\u00ED. V tomto ohledu se popsan\u00E1 aktivace pam\u011Bti podob\u00E1 lidsk\u00E9 epizodick\u00E9 pam\u011Bti, kter\u00E1 na zv\u00ED\u0159atech je velmi obt\u00ED\u017En\u011B modelovateln\u00E1.Vzhledem k tomu, \u017Ee dosud nejsou zn\u00E1my nervov\u00E9 mechanizmy tohoto jevu, projekt klade z\u00E1kladn\u00ED ot\u00E1zky je\u017E umo\u017En\u00ED posouzen\u00ED jeho univerz\u00E1lnosti pro r\u016Fzn\u00E9 typy pam\u011Bti- pasivn\u00ED vyhnut\u00ED a kontextu\u00E1ln\u00ED a t\u00F3nov\u00E9 podmi\u0148ov\u00E1n\u00ED. V dal\u0161\u00ED \u010D\u00E1sti je c\u00EDlem projektu" . . "1"^^ . "0"^^ . "1"^^ . . "Neuvedeno."@en . "http://www.isvav.cz/projectDetail.do?rowId=GP309/04/P206"^^ . . . . "The proposed project focuses on research of the newly described phenomenon of the Out-of-Context Activation of Memory (OCAM) in rat. Our recent experiments show that the highly stressful experience of forced swim for 20 min activates the one-day-oldmemory for the left/right discrimination in the Y-maze. The importance of this phenomenon is based on fact that the situation of Y-maze acquisition is substantially different in its context form the experience of forced swim. The current opinions in thefield of the memory research, however, holds the presentation of sensory stimuli contextually related to the memory acquisition necessary for activation of memory. In this sense, the OCAM resembles the human episodic memory, which is problematic to modelin laboratory animals. Given that the knowledges about mechanisms of the OCAM are still relatively weak, the project asks fundamental questions about the universality of OCAM for different types of memory: the passive avoidance and the fear conditioning"@en . . "Out-of-Context-Activation of Memory- reconsolidation and memory types involved"@en . . . . . .