. "The project gone according to plan both in terms of expertise and in terms of disbursement of funds."@en . . "GP206/09/P470" . . . "The innate immune system of insects includes cellular and humoral reactions. In regulation of these reactions, eicosanoids - metabolites of arachidonic acid, play an important role. Their production can be modulated using eicosanoid biosynthesis inhibitors (EBI). The main aim of this project is to study insect immune system (reactive oxygen and nitrogen metabolites production, hemolymph antibacterial activity, phenoloxidase activity, lysozyme content, hemolymph protein profiles and interactions with Photorhabdus bacteria) using the wax moth Galleria mellonella as a model and modulation of the immune system parameters under inhibition of different pathways of eicosanoid biosynthesis (using different EBIs). The specific role of the particular pathway(s) will be investigated, and effective antibacterial inhibitors/stimulators will be selected with regard to their possible use in agriculture and breeding."@en . " imunita" . . . . . . "2011-04-16+02:00"^^ . . "16"^^ . "Galleria mellonella" . "16"^^ . . "\u0158e\u0161en\u00ED projektu prob\u011Bhlo podle pl\u00E1nu jak z hlediska odborn\u00E9ho tak i z hlediska \u010Derp\u00E1n\u00ED finan\u010Dn\u00EDch prost\u0159edk\u016F."@cs . . "2015-03-02+01:00"^^ . " eikosanoidy" . "http://www.isvav.cz/projectDetail.do?rowId=GP206/09/P470"^^ . "0"^^ . "2011-12-31+01:00"^^ . . "C\u00EDlem je studium imunitn\u00EDho syst\u00E9mu hmyzu (produkce RKM a RDM hemocyty, antibakteri\u00E1ln\u00ED aktivita hemolymfy, aktivita phenoloxid\u00E1zy, mno\u017Estv\u00ED lysozymu a proteinov\u00E9 zm\u011Bny v hemolymf\u011B, interakce s entomopatogenn\u00EDmi bakteriemi rodu Photorhabdus) po p\u016Fsoben\u00ED inhibitor\u016F r\u016Fzn\u00FDch drah biosynt\u00E9zy eikosanoid\u016F" . "2009-01-01+01:00"^^ . "0"^^ . . "Vliv inhibitor\u016F biosynt\u00E9zy eikosanoid\u016F na imunitu zav\u00EDje\u010De voskov\u00E9ho Galleria mellonella" . "1"^^ . . . . . . "Galleria mellonella; imunita; eikosanoidy; inhibitor"@en . "The influence of the eicosanoid biosynthesis inhibitors to immunity of the wax moth Galleria mellonella"@en .