. . "5"^^ . . "5"^^ . . "2011-12-31+01:00"^^ . "2009-01-01+01:00"^^ . "kapil\u00E1rn\u00ED dvoudimenzion\u00E1ln\u00ED separace; kapil\u00E1rn\u00ED elektrofor\u00E9za; prekoncentrace vzorku; laserem indukova"@en . "kapil\u00E1rn\u00ED dvoudimenzion\u00E1ln\u00ED separace" . "0"^^ . "GP203/09/P485" . "\u0158e\u0161en\u00ED projektu prob\u011Bhlo na vynikaj\u00EDc\u00ED \u00FArovni, a to jak z hlediska odborn\u00E9ho tak i z hlediska \u010Derp\u00E1n\u00ED finan\u010Dn\u00EDch prost\u0159edk\u016F."@cs . . "2015-03-02+01:00"^^ . "2011-04-16+02:00"^^ . . "1"^^ . . "Z\u00E1m\u011Brem je prov\u00E1d\u011Bn\u00ED dvourozm\u011Brn\u00FDch separac\u00ED komplexn\u00EDch sm\u011Bs\u00ED biomolekul v kapil\u00E1rn\u00EDm m\u011B\u0159\u00EDtku zalo\u017Een\u00FDch na propojen\u00ED dvou elektrosepara\u010Dn\u00EDch metod o rozd\u00EDln\u00E9 selektivit\u011B. Pro zv\u00FD\u0161en\u00ED citlivosti bude fluorescen\u010Dn\u00ED detekce kombinov\u00E1na s nov\u00FDmi gradientov\u00FDmi elektrofokusa\u010Dn\u00EDmi metodami." . "http://www.isvav.cz/projectDetail.do?rowId=GP203/09/P485"^^ . . "0"^^ . . " kapil\u00E1rn\u00ED elektrofor\u00E9za" . . . . "The project was excellent, both in terms of expertise and in terms of disbursement of funds."@en . " prekoncentrace vzorku" . "The intention is to perform on-line coupling of two separation methods in the capillary format. Resulting two-dimensional (2D) separation is expected to have high efficiency and good detection sensitivity. High peak capacity will be achieved by a combination of\u00A0electroseparation methods based on different separation principles with high degree of orthogonality. Detection sensitivity will be addressed by a laser induced fluorescence (LIF) detection in conjunction with on-line preconcentration of\u00A0 the sample in the first dimension of the separation.\u00A0The research will be preferably focused on temperature-gradient electrofocusing method, which is rather new method combining focusing and separation effects. Application field for 2D microscale separations is in the analysis of biosamples, such as proteomic or metabolomic samples, the inherent complexity of which is a serious challenge for established one-dimensional methods such as HPLC or capillary electrophoresis."@en . . . . . "Dvourozm\u011Brn\u00E9 separa\u010Dn\u00ED techniky pro bioanal\u00FDzu v mikrom\u011B\u0159\u00EDtku" . . . . "Two-dimensional separation techniques for microscale bioanalysis"@en .