. . . "http://www.isvav.cz/projectDetail.do?rowId=GP203/04/P126"^^ . "Suggested project deals with possibilities of the formation of MS/MS libraries using soft ionization techniques. The negative-ion electrospray ionization will be used for anionic dyes studied. The formation of MS/MS libraries for soft ionization techniques is quite rare except for biomolecules due to the limited transferability of results among various mass analyzers. Therefore, the first goal of the project is a definition of the standard measurement conditions allowing the comparison of measured spectra among the ion traps from different manufacturers. The acquired results will be also compared with MS/MS spectra measured on different types of mass analyzers (e.g. triple quadrupole) with the aim to determine the differences and the level of results transferability among various mass analyzers. Three different collision energies will be applied for MS/MS measurements on the ion trap to improve the comparison with the results measured on the triple quadrupole, where the higher"@en . . "V r\u00E1mci \u0159e\u0161en\u00ED grantov\u00E9ho projektu bylo publikov\u00E1no 5 \u010Dl\u00E1nk\u016F v renomovan\u00FDch mezin\u00E1rodn\u00EDch \u010Dasopisech a prezentov\u00E1no 9 p\u0159\u00EDsp\u011Bvk\u016F na mezin\u00E1rodn\u00EDch konferenc\u00EDch, 2 dal\u0161\u00ED \u010Dl\u00E1nky jsou v \u0159\u00EDzen\u00ED. V pr\u016Fb\u011Bhu \u0159e\u0161en\u00ED projektu byla zm\u011B\u0159ena a zinterpretov\u00E1na tandemov"@cs . . "2007-10-16+02:00"^^ . . "Neuvedeno."@en . . "Navrhovan\u00FD projekt se zab\u00FDv\u00E1 studiem mo\u017Enost\u00ED tvorby knihoven MS/MS spekter s pou\u017Eit\u00EDm \u0161etrn\u00FDch ioniza\u010Dn\u00EDch technik. Pro studovan\u00E1 anionick\u00E1 barviva bude pou\u017Eita ionizace elektrosprejem p\u0159i z\u00E1znamu z\u00E1porn\u00FDch iont\u016F. Tvorba MS/MS knihoven s vyu\u017Eit\u00EDm \u0161etrn\u00FDch ioniza\u010Dn\u00EDch technik se krom\u011B biomolekul doposud pou\u017E\u00EDv\u00E1 z\u0159\u00EDdka kv\u016Fli omezen\u00E9 p\u0159enositelnosti v\u00FDsledk\u016F mezi r\u016Fzn\u00FDmi typy analyz\u00E1tor\u016F, a proto prvn\u00EDm c\u00EDlem projektu bude snaha o nalezen\u00ED standardn\u00EDch podm\u00EDnek m\u011B\u0159en\u00ED, ze kter\u00FDch by nam\u011B\u0159en\u00E1 spektrabyla srovnateln\u00E1 pro iontov\u00E9 pasti r\u016Fzn\u00FDch v\u00FDrobc\u016F. Z\u00EDskan\u00E9 v\u00FDsledky budou porovn\u00E1ny i s MS/MS spektry zm\u011B\u0159en\u00FDmi na jin\u00FDch typech hmotnostn\u00EDch analyz\u00E1tor\u016F (nap\u0159. trojit\u00FD kvadrup\u00F3lov\u00FD analyz\u00E1tor, line\u00E1rn\u00ED iontov\u00E1 past) a ur\u010Deny rozd\u00EDly a stupe\u0148 p\u0159evoditelnosti v\u00FDsledk\u016F mezi r\u016Fzn\u00FDmi typy analyz\u00E1tor\u016F. Spektra budou m\u011B\u0159ena p\u0159i t\u0159ech r\u016Fzn\u00FDch kolizn\u00EDch energi\u00EDch kv\u016Fli zlep\u0161en\u00ED mo\u017Enosti porovn\u00E1n\u00ED s v\u00FDsledky m\u011B\u0159en\u00FDmi na trojit\u00E9m kvadrup\u00F3lu, kde lze o\u010Dek\u00E1vat vy\u0161\u0161\u00ED intenzitu fragmentov\u00FDch iont\u016F s" . "Tandem mass spectral libraries of anionic dyes"@en . "Knihovny tandemov\u00FDch hmotnostn\u00EDch spekter anionick\u00FDch barviv" . "0"^^ . . . "The work on this grant project has resulted in 5 articles in renowned international journals and 9 contributions at international conferences, 2 other articles are in progress. Tandem mass spectra of several hundreds of organic dyes, intermediates, degra"@en . . "0"^^ . . . "1"^^ . . . . . "GP203/04/P126" . "12"^^ . . . . "12"^^ .