. "Vysok\u00E9 koncentrace t\u011B\u017Ek\u00FDch kov\u016F v prost\u0159ed\u00ED jsou z\u00E1va\u017Enou p\u0159ek\u00E1\u017Ekou pro \u017Eivot v\u011Bt\u0161iny \u017Eiv\u00FDch organizm\u016F. Rostliny, kter\u00E9 dok\u00E1\u017Eou p\u0159e\u017E\u00EDvat v kontaminovan\u00FDch oblastech jsou na tuto skute\u010Dnost adaptov\u00E1ny. Zp\u016Fsob, jak\u00FDm dok\u00E1\u017Eou r\u016Fst v t\u011Bchto lokalit\u00E1ch je \u010Dasto k\u00F3dov\u00E1n v jejich genomech. Jednou z prvn\u00EDch rostlin, u kter\u00E9 byla tato schopnost adaptace pozorov\u00E1na je Silenka dvoudom\u00E1. Silenka dvoudom\u00E1 je schopna p\u0159e\u017E\u00EDvat na lokalit\u00E1ch s vysok\u00FDm obsahem m\u011Bdi a kadmia. Anal\u00FDzou a srovn\u00E1n\u00EDm transkriptom\u016F rostlin Silenky dvoudom\u00E9 z kontaminovan\u00E9 a nekontaminovan\u00E9 oblasti chceme zjistit, kter\u00E9 geny jsou zodpov\u011Bdn\u00E9 za toleranci k t\u011B\u017Ek\u00FDm kov\u016Fm, zejm\u00E9na m\u011Bdi, a jak se li\u0161\u00ED jejich exprese v ko\u0159enech a nadzemn\u00ED \u010D\u00E1sti. Kombinac\u00ED dat z nov\u00FDch sekvena\u010Dn\u00EDch technologi\u00ED a tradi\u010Dn\u00EDch genomick\u00FDch p\u0159\u00EDstup\u016F budou odhaleny nov\u00E9 geny a genetick\u00E9 dr\u00E1hy zodpov\u011Bdn\u00E9 za fyziologii t\u011B\u017Ek\u00FDch kov\u016F u Silenky dvoudom\u00E9." . . . . . "GP13-34962P" . "Silenka dvoudom\u00E1 jako modelov\u00E1 rostlina pro studium tolerance k t\u011B\u017Ek\u00FDm kov\u016Fm" . " comparative genomics" . " copper" . . . . "http://www.isvav.cz/projectDetail.do?rowId=GP13-34962P"^^ . . . "Silene dioica, heavy metal tolerance, copper, comparative genomics,"@en . "Silene dioica as a model species for heavy metal tolerance"@en . "2014-04-07+02:00"^^ . . "Silene dioica" . . "2015-12-31+01:00"^^ . . . . "0"^^ . " heavy metal tolerance" . "High concentrations of heavy metals in the environment, for example in mining areas, is a serious threat to many organisms. On the other hand, plants which thrive in such localities have adapted to the high concentrations of heavy metals in the soil often through coding by their genomes. Silene dioica is one of the first plants in which adaptation to high concentrations of heavy metals was found. S. dioica can grow on soils with high concentrations of copper and cadmium. By transcriptome analysis and comparison of S. dioica plants from contaminated and uncontaminated localities we will be able to determine which genes are responsible for the heavy metal tolerance, especially to copper, and how the expression patterns differ in roots and shoots and between individual plant populations. A combination of next generation sequencing data with traditional molecular genomic methods will reveal new genes and the genetic pathways involved in the heavy metal physiology of S. dioica."@en . . "1"^^ . "2015-02-09+01:00"^^ . "2013-02-01+01:00"^^ . . "1"^^ . "0"^^ . "1"^^ . . .