. "All of the evidence from animal and human studies showed that there are risks associated with inhalation of nano-sized particles (NSP). The alveolar translocation of NSP is likely the pathway how NSP can be transposed from air to the blood vessels, and distributed throughout the body to organs. In spite of the fact that an extrapulmonary translocation is highly dependent on particle surface characteristics/chemistry, in addition to particle size, the study of transport of inhalated nano-particles\u00A0Pb, Cd\u00A0(elements, oxides), their allocations in organs, as well as study of toxicity\u00A0these nanoparticles\u00A0will be carry out with nanoparticles (10, 20 and 60 nm).\u00A0\u00A0\u00A0\u00A0\u00A0\u00A0 The nonbiogenous elements (Cd, Pb) have been selected as products of technological processes and due to their presence in ambient aerosol. The research will give us more information for a proper understanding of risks of technologies producing\u00A0Cd and Pb nano-sized particles\u00A0and ambient aerosol risk.\u00A0"@en . "Existuje re\u00E1ln\u00FD a nevy\u0159e\u0161en\u00FD probl\u00E9m spojen\u00FD s inhalac\u00ED aerosol\u016F, kter\u00E9 maj\u00ED charakter nano\u010D\u00E1stic. P\u0159i inhalaci jsou tyto miniaturn\u00ED objekty transportov\u00E1ny do krevn\u00EDho \u0159e\u010Di\u0161t\u011B a d\u00E1le do jednotliv\u00FDch org\u00E1n\u016F, v nich\u017E se mohou ukl\u00E1dat. \u00DA\u010Dinnost\u00A0transportu z\u00E1vis\u00ED vedle velikosti \u010D\u00E1stic tak\u00E9\u00A0na jejich chemick\u00FDch a povrchov\u00FDch vlastnostech. V projektu se zam\u011Br\u00EDme\u00A0na studium transportu\u00A0a akumulace nano\u010D\u00E1stic (10-60 nm), kter\u00E9 jsou slo\u017Een\u00E9 z prvk\u016F nebo oxid\u016F (Cd, Pb) nemaj\u00EDc\u00EDch biogenn\u00ED charakter v t\u011Blech inhala\u010Dn\u011B exponovan\u00FDch my\u0161\u00ED.\u00A0Nano\u010D\u00E1stice\u00A0Pb a Cd (prvky, oxidy) jsou produkov\u00E1ny p\u0159i r\u016Fzn\u00FDch technolgick\u00FDch\u00A0procesech a\u00A0pat\u0159\u00ED k\u00A0v\u00FDznamn\u00FD polutant\u016Fm\u00A0\u017Eivotn\u00EDho prost\u0159ed\u00ED." . . . "2015-04-23+02:00"^^ . . . "Study of transport of inhalated nano-sized particles (Pb, Cd) and their allocation in organs"@en . . "http://www.isvav.cz/projectDetail.do?rowId=GAP503/11/2315"^^ . . . "2011-01-01+01:00"^^ . . . "0"^^ . . . "inhalated nano-sized particles allocation organs"@en . "28"^^ . "Studium transportu inhalovan\u00FDch nano\u010D\u00E1stic (Pb, Cd) a jejich lokalizace v org\u00E1nech" . "28"^^ . . "GAP503/11/2315" . . . "2015-12-31+01:00"^^ . . "1"^^ . . "2"^^ .