"Centre for genomics"@en . "1"^^ . "Centrum genomiky" . . . "0"^^ . "2"^^ . "The aim of this project is to create a Centre for Genomics. In this Centre the complex genomics would be developed. The Department of Gene Structure and Expression gained the experience in international genome projects and is now engaged in sequencing bacterial genomes. In collaboration with the University of Chicago is now developing advanced bioinformatics tools. The functional genomics of mouse is performed by J. Forejt and P.M. Mal\u00FD. These two projects complement expertise of these groups and can lead to sequencing genomes and plasmids of biotechnologically important bacteria on one side and large mouse genome regions on the other side. This program will be accelerated by advances in methodology of microarrays. This methodology is being developed at the Institute of Inherited Deseases at Charles University. The group of M. Elleder is ready to expand at this program from diagnostics to more general projects such as studies of gene expression in bacteria and mammals. Genomics is a new field of scien"@en . "2"^^ . "0"^^ . . . "Vynikaj\u00EDc\u00ED pln\u011Bn\u00ED."@cs . . . . . "http://www.isvav.cz/projectDetail.do?rowId=GA301/99/M023"^^ . . . . "GA301/99/M023" . . . . "Navrhuje se z\u0159\u00EDdit Centrum genomiky. Z\u00E1kladn\u00EDm pracovi\u0161t\u011Bm tohoto Centra by byl \u00DAstav molekul\u00E1rn\u00ED genetiky AV \u010CR, kter\u00FD by smluvn\u011B spolupracoval s \u00DAstavem d\u011Bdi\u010Dn\u00FDch metabolick\u00FDch poruch 1. LF UK. Krom\u011B toho by nesmluvn\u011B spolupracoval s odd\u011Blen\u00EDm lidsk\u00E9 genetiky 2. LF UK a s Laborato\u0159\u00ED molekul\u00E1rn\u00ED embryologie Mendelovy zem\u011Bd\u011Blsk\u00E9 university v Brn\u011B. Toto centrum by nav\u00EDc bylo propojeno s Centrem molekul\u00E1rn\u00ED genetiky V\u0160CHT Praha. Vznikl by tak komplex pracovi\u0161\u0165 strukturn\u00ED genomiky, bioinformatiky a funk\u010Dn\u00EDgenomiky. Jednotliv\u00E9 tematiky by se vz\u00E1jemn\u011B dopl\u0148ovaly. Centrum by slou\u017Eilo jako \u0161kola doktorsk\u00FDch studi\u00ED pro v\u00FDchovu odborn\u00EDk\u016F, jejich\u017E uplatn\u011Bn\u00ED se v budoucnu d\u00E1 s jistotou o\u010Dek\u00E1vat v biotechnologi\u00EDch, l\u00E9ka\u0159sk\u00FDch oborech, soudnictv\u00ED a kriminalistice. Genomika byla v minulosti v \u010CR velmi zanedb\u00E1na zejm\u00E9na d\u00EDky na\u0161\u00ED \u00FApln\u00E9 izolaci od sv\u011Btov\u00E9 v\u011Bdy v dob\u011B (70 a 80 l\u00E9ta), kdy vznikaly jej\u00ED z\u00E1klady. P\u0159itom se jedn\u00E1 o obor bez n\u011Bho\u017E se v budoucnu neobejde ani medic\u00EDna ani modern\u00ED pr\u016Fmysl a zem\u011Bd\u011Blstv\u00ED. Tent" . .