. "2016-12-31+01:00"^^ . "polyurethanes, elasticity, biodegradability, mechanical properties, atomic force microscopy"@en . "http://www.isvav.cz/projectDetail.do?rowId=GA13-06700S"^^ . "4"^^ . "0"^^ . . . . "Multifunctional highly elastic polymeric materials with controlled biodegradability"@en . "4"^^ . . "polyurethanes" . . "0"^^ . . . . " biodegradability" . . "Budou vyv\u00EDjeny a charakterizov\u00E1ny v\u00EDceslo\u017Ekov\u00E9 materi\u00E1ly na b\u00E1zi polyurethan\u016F s c\u00EDlen\u00FDmi u\u017Eitn\u00FDmi vlastnostmi (nap\u0159. vysok\u00FDm stupn\u011Bm elasticity a \u0159\u00EDzenou biodegradabilitou) pro jejich potencion\u00E1ln\u00ED praktick\u00E9 vyu\u017Eit\u00ED v medic\u00EDn\u011B. Polyurethanov\u00E9 elastomery, vyzna\u010Duj\u00EDc\u00ED se vysok\u00FDm stupn\u011Bm f\u00E1zov\u00E9 separace, budou obsahovat degradovateln\u00E9 sekvence jak v m\u011Bkk\u00E9, tak tvrd\u00E9 f\u00E1zi. Stupe\u0148 degradability bude \u0159\u00EDzen obsahem a charakterem n\u00EDzkomolekul\u00E1rn\u00EDch nebo oligomern\u00EDch sekvenc\u00ED na b\u00E1zi L-laktidu nebo kaprolaktonu. Dal\u0161\u00EDmi z\u00E1kladn\u00EDmi surovinami budou alifatick\u00E9 polykarbon\u00E1tdioly, diisokyan\u00E1ty a prodlu\u017Eova\u010De \u0159et\u011Bzce. C\u00EDlem projektu je nal\u00E9zt a objasnit vztahy mezi v\u00FDb\u011Brem v\u00FDchoz\u00EDch surovin, postupem p\u0159\u00EDpravy a fin\u00E1ln\u00EDmi vlastnostmi t\u011Bchto materi\u00E1l\u016F. D\u016Fraz je kladen p\u0159edev\u0161\u00EDm na podrobnou anal\u00FDzu mechanick\u00FDch vlastnost\u00ED, zejm\u00E9na na korelaci makroskopick\u00FDch vlastnost\u00ED (tahov\u00E9 zkou\u0161ky) s mechanick\u00FDmi vlastnostmi na \u00FArovni nano- a\u017E mikrometr\u016F (anal\u00FDza mikroskopi\u00ED atom\u00E1rn\u00EDch sil). Zvolen\u00E9 metody charakterizace umo\u017En\u00ED sledovat i tvorbu meziprodukt\u016F nebo produkt\u016F vedlej\u0161\u00EDch reakc\u00ED." . "Advanced polyurethane-based materials with desired and targeted properties (the high elasticity and the controlled biodegradability) will be prepared and characterized, for potential practical use in medical applications. Polyurethane elastomers featuring high phase separation will contain degradable sequences both in soft and hard segments. The degradability degree will be controlled by the contents and character of low-molecular or oligomeric building units based on L-lactide or caprolactone. Aliphatic polycarbonates, diisocyanates and chain extenders will be used as other starting materials. The main goal is the elucidation and understanding the relations between the composition, technique of preparation and functional properties of polyurethane products prepared. Detailed mechanical analysis will be important part of the project, especially the correlation of macroscopic (tensile) properties with that on nano- and micrometre scale detected by atomic force microscopy. Experimental methods are chosen in order to study and characterize intermediate- and by- products as well."@en . "2015-04-23+02:00"^^ . . . . "2014-03-31+02:00"^^ . . "2013-02-01+01:00"^^ . . . " elasticity" . "1"^^ . "Multifunk\u010Dn\u00ED vysoce elastick\u00E9 polymern\u00ED materi\u00E1ly s \u0159\u00EDzenou biodegradabilitou" . " mechanical properties" . . "GA13-06700S" .