. . "2011-12-31+01:00"^^ . . . "http://www.isvav.cz/projectDetail.do?rowId=GA106/09/0734"^^ . . "20"^^ . "The proposed project aims to model mechanical properties of living tissues by using the scale approaches (microcontinuum) in order to include parameters of cellular cytoskeleton into the resulting continuum models. To reveal an influence of various features of the cytoskeleton on mechanical behavior of tissues, we will apply several approaches modelling the cytoskeleton (as a tensegrity structure, semiflexible polymer network, and ontinuum structure with the rheology of soft glassy materials). Resulting continuum models of tissues will be tested by means of measurement of mechanical properties of macroscopic tissue samples which microscopic structure will be modified by chemical interventions (leading for instance to %22switching off%22 of various components of the cytoskeleton). Microscopic structure of tissue will be investigated and evaluated by modernstereological methods as well as the confocal microscopy. Resulting continuum models will be used in modeling of smooth muscle within wall of veins and biomechanics of corio-epidermal suspension of the distal phalanx in horse."@en . . " cytoskeleton" . "biomechanika tk\u00E1n\u00ED, cytoskeleton, mechanick\u00E9 vlastnosti \u017Eiv\u00FDch tk\u00E1n\u00ED"@en . . "2011-04-16+02:00"^^ . "20"^^ . . . . . "0"^^ . . "2009-01-01+01:00"^^ . . . "Relation among microscopic arrangement of biological tissues, function of cytoskeleton, and mechanical properties of living"@en . "1"^^ . . "2015-03-02+01:00"^^ . "1"^^ . "Vytvo\u0159en\u00ED po\u010D\u00EDta\u010Dov\u00E9ho modelu vybran\u00FDch \u017Eiv\u00FDch tk\u00E1n\u00ED s r\u016Fzn\u00FDmi modely bun\u011B\u010Dn\u00E9ho cytoskeletu tak, aby bylo mo\u017Eno testovat vliv r\u016Fzn\u00FDch aspekt\u016F cytoskeletu na mechanick\u00E9 chov\u00E1n\u00ED tk\u00E1n\u00ED. Modely identifikovat a testovat mechanick\u00FDmi m\u011B\u0159en\u00EDmi tk\u00E1n\u00ED dopln\u011Bn\u00FDmi stereologick\u00FDm a mikroskopick\u00FDm vyhodnocen\u00EDm." . "\u0158e\u0161en\u00ED projektu prob\u011Bhlo podle pl\u00E1nu jak z hlediska odborn\u00E9ho tak i z hlediska \u010Derp\u00E1n\u00ED finan\u010Dn\u00EDch prost\u0159edk\u016F."@cs . "GA106/09/0734" . . "Vliv mikroskopick\u00E9ho uspo\u0159\u00E1d\u00E1n\u00ED tk\u00E1n\u00ED a funkce bun\u011B\u010Dn\u00E9ho cytoskeletu na mechanick\u00E9 vlastnosti \u017Eiv\u00FDch tk\u00E1n\u00ED" . "biomechanika tk\u00E1n\u00ED" . "The project gone according to plan both in terms of expertise and in terms of disbursement of funds."@en . . .