. "*IgY jsou imunoglobuliny charakteru protil\u00E1tek, kter\u00E9 v prvn\u00EDch dnech po vyl\u00EDhnut\u00ED zaji\u0161\u0165uj\u00ED novorozen\u00FDm pta\u010D\u00EDm ml\u00E1\u010Fat\u016Fm specifickou pasivn\u00ED imunitu. Svoj\u00ED strukturou a zejm\u00E9na pak funkc\u00ED se v\u00FDznamn\u011B neli\u0161\u00ED od podobn\u00FDch imunoglobulin\u016F savc\u016F v\u010Detn\u011B \u010Dlov\u011Bka.V\u011Bt\u0161ina existuj\u00EDc\u00EDch prepar\u00E1t\u016F, kter\u00E9 jsou vytvo\u0159en\u00E9 na b\u00E1zi IgY protil\u00E1tek sm\u011B\u0159uj\u00ED k l\u00E9\u010Db\u011B st\u0159evn\u00EDch infekc\u00ED je v sou\u010Dasnosti zam\u011B\u0159ena sp\u00ED\u0161e na peror\u00E1ln\u00ED pou\u017Eit\u00ED. Podstatn\u011B men\u0161\u00ED pozornost byla v\u011Bnov\u00E1na jejich pou\u017Eit\u00ED pro l\u00E9\u010Dbu a prevenci lok\u00E1n\u00EDch infekc\u00ED k\u016F\u017Ee a sliznic. Nemnoh\u00E9 pokusy zam\u011B\u0159en\u00E9 t\u00EDmto sm\u011Brem v\u0161ak poukazuj\u00ED na \u0161irok\u00E9 mo\u017Enosti jejich vyu\u017Eit\u00ED i v t\u00E9to aplika\u010Dn\u00ED oblasti.C\u00EDlem projektu je vyu\u017Eit\u00ED IgY protil\u00E1tek ve v\u00FDvoji p\u0159\u00EDpravku k l\u00E9\u010Db\u011B a prevenci lok\u00E1ln\u00EDch ko\u017En\u00EDch infekc\u00ED zp\u016Fsoben\u00FDch nej\u010Dast\u011Bj\u0161\u00EDmi p\u016Fvodci infek\u010Dn\u00EDch dermatitid (tito p\u016Fvodci se \u010D\u00EDm d\u00E1le, t\u00EDm v\u00EDce st\u00E1vaj\u00ED rezistentn\u00ED v\u016F\u010Di p\u016Fsoben\u00ED antibiotik a ostatn\u00EDch chemoterapeutik)" . . . . "FR-TI1/205" . . "The proj. resulted in a new original topically applicable product for treatment of acne vulgaris and skin inflammation.The preparation is based on natural ingredients.The key ingredient is IGY antibodies obtained fromEGG Yolks produced by immunized hens."@en . . "antibodies IgY; skin infections; ointment"@en . "0"^^ . "2014-07-14+02:00"^^ . . "0"^^ . . "2012-12-31+01:00"^^ . "2"^^ . "antibodies IgY" . "2"^^ . . "1"^^ . "2009-07-01+02:00"^^ . "*V\u00FDvoj prepar\u00E1tu s obsahem protil\u00E1tek IgY pro lok\u00E1ln\u00ED terapii ko\u017En\u00EDch infekc\u00ED" . "V\u00FDsledkem projektu je nov\u00FD topicky aplikovateln\u00FD p\u0159\u00EDpravek proti akn\u00E9 a ko\u017En\u00EDm z\u00E1n\u011Bt\u016Fm. Prepar\u00E1t je zalo\u017Een na p\u0159\u00EDrodn\u00EDch slo\u017Ek\u00E1ch, z nich\u017E kl\u00ED\u010Dovou roli hraj\u00ED IGY protil\u00E1tky z\u00EDskan\u00E9 z vaje\u010Dn\u00FDch \u017Eloudk\u016F imunizovan\u00FDch nosnic."@cs . . "http://www.isvav.cz/projectDetail.do?rowId=FR-TI1/205"^^ . . . . . . . . "2012-04-12+02:00"^^ . . " skin infections" . . "*IgY are immonuglobulins behaving as antibodies. Their natural role is to ensure the specific passive immunity in the first days in life of new born birds. Their structure and especially their function is not much different form the similar immunoglobulins of mammals including the humans.Most of the existing preparates, which are made on IgY antidotes base and which are used for medication of intestinal infections have been currently focused mainly on per oral application. Further less attention has been given to their use for medication and prevention of local dermatic infections of skin and mucosas.The project goal focuses on using of IgY antibodies with the aim to develop a special preparate which will be used as a medicine or prevention against dermal infections caused by the most common causer of infectious dermatitis (these causers have slowly become resistant against the antibiotics or other chemotherapeutics)"@en . "*Development of preparate with the conntent of IgY antibodies used for local dermatic infections therapy"@en .