. . . . . "*The reconstruction of the connective tissue (joint cartilage and ligaments) after their injury or the degeneration belongs to the most perspective and frequently used methods in the surgery of the locomotive apparatus. The project solves the improvement of the surgical technique when scaffold for the connective tissue is used, even at the endoscopically performed surgery. The proposal suggests the development of the biodegradable scaffold, performing tests of the scaffold, its properties, the construction of the prototype and performing the series of pre-clinical tests. Authors emphasize the maximum easy function and safety of the whole surgical procedure."@en . . "*Nanotechnology in medicine - tissue support for bidner reconstruction."@en . . "6"^^ . "6"^^ . . "connective tissue; cartilage; ligament; scaffold; reconstruction"@en . . . " cartilage" . "connective tissue" . "http://www.isvav.cz/projectDetail.do?rowId=FI-IM4/205"^^ . "2010-05-28+02:00"^^ . "0"^^ . "2010-10-30+02:00"^^ . "2011-06-22+02:00"^^ . . "*Nanotechnologie v medic\u00EDn\u011B - tk\u00E1\u0148ov\u00FD nosi\u010D pro rekonstrukce pojiva." . . "1"^^ . . "FI-IM4/205" . "1"^^ . . " ligament" . "2007-03-01+01:00"^^ . " scaffold" . . "*Rekonstrukce pojivov\u00FDch tk\u00E1n\u00ED (kloubn\u00EDch chrupavek a vaz\u016F) po zran\u011Bn\u00ED nebo jejich degeneraci pat\u0159\u00ED k nejperspektivn\u011Bj\u0161\u00EDm a nej\u010Dast\u011Bji pou\u017E\u00EDvan\u00FDm chirurgick\u00FDm z\u00E1krok\u016Fm na pohybov\u00E9m apar\u00E1tu. C\u00EDlem projektu je zlep\u0161en\u00ED chirurgick\u00FDch z\u00E1krok\u016F v p\u0159\u00EDpad\u011B pou\u017Eit\u00ED scaffoldu, dokonce i p\u0159i endoskopii. Projekt zahrnuje v\u00FDvoj biodegradabiln\u00EDho scaffoldu, prov\u00E1d\u011Bn\u00ED test\u016F na scaffoldu, studium jeho vlastnost\u00ED, v\u00FDrobu prototypu a prov\u00E1d\u011Bn\u00ED preklinick\u00FDch test\u016F. Auto\u0159i zd\u016Fraz\u0148uj\u00ED jednoduchost a bezpe\u010Dnost cel\u00E9 procedury." . . . "Hydrogel was prepared from chamically modified imaluronane, including ceus. Production of extracellular matrix was observed. Than seeded hydrogel was implaned into the join of experimental animal and the reaction of cartilage tissue was observed."@en . "Z chemicky modifikovan\u00E9ho imalyronanu byl p\u0159ipraven hydrogel s bu\u0148kami a sledov\u00E1na produkce extracelul\u00E1rn\u00ED matrix. N\u00E1sledn\u011B byl oset\u00FD hydrogel vlo\u017Een do kloubu experiment\u00E1ln\u00EDho zv\u00ED\u0159ete a sledov\u00E1na reakce chrupav\u010Dit\u00E9 tk\u00E1n\u011B."@cs . .