. "7E09031" . . "1"^^ . " mesenchymal stem cells" . "0"^^ . "2012-07-12+02:00"^^ . "2009-11-01+01:00"^^ . "0"^^ . . . "Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization." . "Stem cells offer a promising avenue to therapy for a wide range of complaints. However, for this potential to be realized, a consistent and plentiful supply of well-characterised stem cells is essential. There has been relatively little progress in the development of new culture technologies for the large-scale manufacture of mesenchymal stem cells (MSCs). There are no standards for characterisation, isolation or identification of MSCs from any tissue, nor are there standard protocols for differentiation of MSCs to various lineages. Additionally, surface markers used for MSC characterization lack specificity and cryopreservation protocols are not standardized. PurStem will: - Identify the MSC \u201Creceptome\u201D and, - Use this repertoire of growth factor receptors to, - Develop novel serum-free media for MSC production."@en . . "0"^^ . "Utilisation of the mesenchymal stem cell receptome for rational development of uniform, serum-free culture conditions and tools for cell characterization."@en . . . "Hodnocen\u00ED v\u00FDsledk\u016F \u0159e\u0161en\u00ED ministerstvo neprov\u00E1d\u00ED, nebo\u0165 podm\u00EDnkou podpory je, \u017Ee uchaze\u010D byl vybr\u00E1n mezin\u00E1rodn\u00EDm poskytovatelem v souladu s pravidly p\u0159\u00EDslu\u0161n\u00E9ho programu. Projekt je hodnocen a\u017E po jeho schv\u00E1len\u00ED mezin\u00E1rodn\u00EDm poskytovatelem."@cs . . . "Stem cells offer a promising avenue to therapy for a wide range of complaints. However, for this potential to be realized, a consistent and plentiful supply of well-characterised stem cells is essential. There has been relatively little progress in the development of new culture technologies for the large-scale manufacture of mesenchymal stem cells (MSCs). There are no standards for characterisation, isolation or identification of MSCs from any tissue, nor are there standard protocols for differentiation of MSCs to various lineages. Additionally, surface markers used for MSC characterization lack specificity and cryopreservation protocols are not standardized. PurStem will: - Identify the MSC \u201Creceptome\u201D and, - Use this repertoire of growth factor receptors to, - Develop novel serum-free media for MSC production." . " serum-free cultivation" . . " differentiation" . . "2011-10-31+01:00"^^ . . "http://www.isvav.cz/projectDetail.do?rowId=7E09031"^^ . . . . "Stem cells" . "Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider."@en . . "2011-03-10+01:00"^^ . . "Stem cells; mesenchymal stem cells; serum-free cultivation; differentiation; phenotypic analysis"@en . . "0"^^ . .