"0"^^ . . "0"^^ . " biomedical research" . "2012-09-30+02:00"^^ . "7E09019" . . . "Hodnocen\u00ED v\u00FDsledk\u016F \u0159e\u0161en\u00ED ministerstvo neprov\u00E1d\u00ED, nebo\u0165 podm\u00EDnkou podpory je, \u017Ee uchaze\u010D byl vybr\u00E1n mezin\u00E1rodn\u00EDm poskytovatelem v souladu s pravidly p\u0159\u00EDslu\u0161n\u00E9ho programu. Projekt je hodnocen a\u017E po jeho schv\u00E1len\u00ED mezin\u00E1rodn\u00EDm poskytovatelem."@cs . " biomarkers" . "2013-06-28+02:00"^^ . . . . " molecular diagnostics" . " sample collection" . . . " diagnostic tools" . . "Standards; pre-analytical phase; in vitro diagnostics; molecular diagnostics; diagnostic tools; biomarkers; biomedical research; blood sample; tumour sample; tissue sample; quality assurance; sample collection; sample handling; sample stabilisation"@en . " in vitro diagnostics" . . "2012-03-19+01:00"^^ . "Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics" . . "Standards" . "In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assay developers, aims at developing quality guidelines for molecular in vitro diagnostics and to standardise the pre-analytical workflow in related procedures. Regarding the second point, SPIDIA aims at developing modern pre-analytical tools for diagnostics improving the stabilisation, handling and study of free biomolecules within blood, plasma, serum, tissues and tumours. Recent discoveries have revealed that RNA, DNA or proteins, released from pathological sites, like tumour cells or Alzheimer\u2019s disease (AD) brain lesions, into the blood or as a secondary blood based response to the disease can serve" . " sample handling" . . "http://www.isvav.cz/projectDetail.do?rowId=7E09019"^^ . . " tumour sample" . . "Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider."@en . " pre-analytical phase" . . "In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assay developers, aims at developing quality guidelines for molecular in vitro diagnostics and to standardise the pre-analytical workflow in related procedures. Regarding the second point, SPIDIA aims at developing modern pre-analytical tools for diagnostics improving the stabilisation, handling and study of free biomolecules within blood, plasma, serum, tissues and tumours. Recent discoveries have revealed that RNA, DNA or proteins, released from pathological sites, like tumour cells or Alzheimer\u2019s disease (AD) brain lesions, into the blood or as a secondary blood based response to the disease can serve"@en . . " quality assurance" . . "2009-10-01+02:00"^^ . " tissue sample" . . "Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics"@en . . "1"^^ . "0"^^ . " blood sample" . "0"^^ .