. . . "1B53009" . "1"^^ . . "2005-02-01+01:00"^^ . "0"^^ . "2009-11-04+01:00"^^ . . "0"^^ . . " histologie" . "43"^^ . "43"^^ . . . " s\u00E9rologick\u00E1 diagnostika" . . . "Avi\u00E1rn\u00ED tuberkul\u00F3za a mykobakteri\u00F3zy: rozvoj metod pro jejich prevenci a tlumen\u00ED studiem zdroj\u016F infekce a patogeneze" . " hygiena potravin" . . . . "tuberkul\u00F3za prasat" . "Avian tuberculosis and mycobacterioses: the development of methods for theirs prevention and eradication by study of mycobacterial sources and pathogenesis of infection"@en . . "Projekt \u0159e\u0161il problematiku p\u0159enosu avi\u00E1rn\u00ED tuberkul\u00F3zy. Projekt \u0159e\u0161il v\u00FDznamnou problematiku n\u00E1kazy p\u016Fvodci tuberkul\u00F3zy. \u0158e\u0161en\u00ED projektu prob\u00EDhalo v souladu se zad\u00E1n\u00EDm."@cs . "The research plan solved the issue of avian tuberculosis transmission. The plan solved a significant issue of the contagion through tuberculosis aetiological agens. Solving the research plan carried out in accordance with the task."@en . . "\u00DA\u010Delem projektu je posouzen\u00ED v\u00FDskytu vybran\u00FDch z\u00E1stupc\u016F komplexu Mycobacterium avium (MAC): M. avium subsp. avium a M. a. hominissuis u zv\u00ED\u0159at a v prost\u0159ed\u00ED v \u010Cesk\u00E9 republice podlo\u017Een\u00FD anal\u00FDzou trend\u016F ve v\u00FDskytu tuberkul\u00F3zn\u00EDch n\u00E1lez\u016F u jate\u010Dn\u00EDch zv\u00ED\u0159at (zejm. skotu a prasat). Pomoc\u00ED bli\u017E\u0161\u00ED identifikace izol\u00E1t\u016F metodami molekul\u00E1rn\u00ED biologie bude sledov\u00E1no jejich \u0161\u00ED\u0159en\u00ED v infikovan\u00E9m st\u00E1du p\u0159\u00EDp. mezi jednotliv\u00FDmi druhy zv\u00ED\u0159at na jedn\u00E9 farm\u011B. Intenzivn\u00EDmi vy\u0161et\u0159ov\u00E1n\u00EDmi na vybran\u00FDch infikovan\u00FDch farm\u00E1ch zv\u00ED\u0159at budou posouzena rizika infekce jednotliv\u00FDch slo\u017Eek potravy a st\u00E1jov\u00E9ho prost\u0159ed\u00ED (stelivo, nap\u00E1jec\u00ED voda, prach, divoc\u00ED pt\u00E1ci, drobn\u00ED zemn\u00ED savci a dal\u0161\u00ED). Pomoc\u00ED experiment\u00E1ln\u00ED infekce prasat ob\u011Bma v\u00FD\u0161e uveden\u00FDmi z\u00E1stupci MAC a dv\u011Bma druhy atypick\u00FDch mykobakt\u00E9ri\u00ED (M. terrae, M. fortuitum) bude studov\u00E1n jejich imunologick\u00FD profil pomoc\u00ED laboratorn\u00EDch test\u016F bu\u0148kami-zprost\u0159edkovan\u00E9 imunity - test blastick\u00E9 transformace a detekce produkce interferonu-gama po in vitro stimulaci specifick\u00FDm antigenem. D\u00E1" . " bun\u011B\u010Dn\u00E1 imunita" . " masn\u00E9 produkty" . "The purpose of the study is an appraisal of occurrence of selected members of Mycobacterium avium complex (MAC): M. avium subsp. avium and M. a. hominisuis in animals and environment in the Czech Republic, based on the analysis of tuberculous lesions inslaughtered animals (mainly cattle and pigs). Detailed identification of isolates by molecular biological methods will be used for monitoring of spreading of mycobacteria in the infected herd, possibly between respective species on one farm. Infection risk of single components of feed and stable environment (litter, drinking water, dust, wild-living birds, small terrestrial mammals etc.) will be assessed by intensive investigations on selected farms with infected animals. During experimental infection of pigs with M. a. avium, M. a. hominisuis and two atypical mycobacteria (M. terrae, M. fortuitum), immunological profile of infected pigs will be studied by laboratory tests of cell-mediated immunity: blastic transformation test and detection of gamma-in"@en . " atypick\u00E9 mykobakt\u00E9rie" . "http://www.isvav.cz/projectDetail.do?rowId=1B53009"^^ . "2008-12-31+01:00"^^ . "2008-03-10+01:00"^^ . . "tuberkul\u00F3za prasat; atypick\u00E9 mykobakt\u00E9rie; s\u00E9rologick\u00E1 diagnostika; bun\u011B\u010Dn\u00E1 imunita; histologie; masn\u00E9 produkty; hygiena potravin; p\u0159e\u017E\u00EDv\u00E1n\u00ED mykobakt\u00E9ri\u00ED"@en . . . .