. . "1"^^ . "1592"^^ . . "\"The purpose of the project is to develop methods for the determination of sperm membrane integrity, which could be used for the prediction of fertilising capacity of ejaculates and AI doses in the field. The studies are based on the detection of the levels of sperm membrane structure disintegration, functional activity of sperm mitochondrial spirals in relation to the motility characteristics, elaboration of \"\"strict\"\" methods of sperm morphological analysis in respect to the morphological resistance test and the effect of adverse factors of the internal and external environment. The comparison of significant values of the levels of binding proteins to acid polysaccharides with the fertilising characteristics of ejaculates will be based on the study of spermadhesins with respect to the functional levels of the sexual accessory glands. The interactions of antisperm antibodies with spermatozoa will be assessed, the alterations in functional characteristics and the changes of superficial membrane structure\""@en . . "spermatozoa"@en . . "1592"^^ . "0"^^ . "The assessment of the membrane and immune interactions of spermatozoa for the prediction of their fertilizing capacity"@en . . "9"^^ . "\"Projekt je zam\u011B\u0159en na vypracov\u00E1n\u00ED provozn\u011B vyu\u017Eiteln\u00FDch metod stanovuj\u00EDc\u00EDch integritu membr\u00E1n spermi\u00ED k predikci fertiliza\u010Dn\u00ED potence ejakul\u00E1t\u016F a ID. Studie se op\u00EDraj\u00ED o stanoven\u00ED \u00FArovn\u011B desintegrace membr\u00E1nov\u00FDch struktur spermi\u00ED, funk\u010Dn\u00ED aktivity mitochondri\u00E1ln\u00ED spir\u00E1ly spermi\u00ED v n\u00E1vaznosti na ukazatele pohyblivosti, stanoven\u00ED \"\"striktn\u00EDch\"\" metod morfologick\u00E9 anal\u00FDzy spermi\u00ED s p\u0159ihl\u00E9dnut\u00EDm k testu morfologick\u00E9 rezistence a vlivu negativn\u011B p\u016Fsob\u00EDc\u00EDch faktor\u016F vnit\u0159n\u00EDho a vn\u011Bj\u0161\u00EDho prost\u0159ed\u00ED. Posouzen\u00ED pr\u016Fkazn\u00E9 hodnoty \u00FArovn\u011B vazebn\u00FDch b\u00EDlkovin na kysel\u00E9 polysacharidy k ukazatel\u016Fm fertilizace ejakul\u00E1t\u016F bude zalo\u017Eeno na studiu spermadhesin\u016F v n\u00E1vaznosti na funk\u010Dn\u00ED \u00FArove\u0148 p\u0159\u00EDdat\u00FDch pohlavn\u00EDch \u017Elaz. Hodnocen\u00ED interakce protil\u00E1tek proti spermi\u00EDm se spermiemi bude spojeno se sledov\u00E1n\u00EDm zm\u011Bn funk\u010Dn\u00EDch ukazatel\u016F a zm\u011Bn na povrchov\u00FDch membr\u00E1nov\u00FDch struktur\u00E1ch. Bude sledov\u00E1na zm\u011Bna antigenicity spermi\u00ED v n\u00E1vaznosti na morfologick\u00E9 aberace. K pr\u016Fkazu fertilizace budou ov\u011B\u0159eny v n\u00E1vaznosti na metodick\u00E9 z\u00E1m\u011Bry testy\""@cs . . "0"^^ . "9"^^ . "Stanoven\u00ED membr\u00E1nov\u00FDch a imunitn\u00EDch interakc\u00ED spermi\u00ED k predikci jejich fertiliza\u010Dn\u00ED potence"@cs . . . . . .