. "The project will include a rather broad scope of topics of clinical immunology and its aim is to recognize the role of impairments of the immune system in the pathogenesis of specific infectious diseases and in disturbances of the general state of healthin animal populations. The proposal of the project is based on the knowledge gained from the preceding research projects and it is intended to extend their application to other health disorders and diseases and further animal species. One of the two par ts of the project will include a screening of impairments of the immune system in cattle and possibly also swine herds, followed by detailed pathogenetic studies of specific infectious diseases (bovine virus diarrhoea and possibly others) associated withthe impairment of the immune system. The other part of the project will deal with diseases of the canine and the feline immune systems, concentrating on the pathogenesis of immunodeficiencies induced by demodicosis and/or pyoderma in dogs, on the monito"@en . "Projekt si klade za c\u00EDl dolo\u017Eit v\u00FDznam poruch imunitn\u00EDho syst\u00E9mu zv\u00ED\u0159at ve vztahu k patogenezi konkr\u00E9tn\u00EDch infek\u010Dn\u00EDch onemocn\u011Bn\u00ED a k naru\u0161en\u00ED celkov\u00E9ho zdravotn\u00EDho stavu v sou\u010Dasn\u00FDch chovech. Navazuje na poznatky dosa\u017Een\u00E9 p\u0159i \u0159e\u0161en\u00ED \u00FAkolu v p\u0159edchoz\u00EDm obdob\u00ED, ale s v\u00FDrazn\u00FDm roz\u0161\u00ED\u0159en\u00EDm na dal\u0161\u00ED poruchy a choroby a v\u00EDce \u017Eivo\u010Di\u0161n\u00FDch druh\u016F. Projekt bude \u0159e\u0161en se zam\u011B\u0159en\u00EDm na skot, m\u00E9n\u011B ji\u017E na psy a ko\u010Dky. V obou bude \u010D\u00E1st \u0159e\u0161en\u00ED v\u011Bnov\u00E1na sledov\u00E1n\u00ED v\u00FDskytu poruch imunitn\u00EDho syst\u00E9mu v sou\u010Dasn\u00FDch populac\u00EDchzv\u00ED\u0159at; u skotu a prasat p\u0159edev\u0161\u00EDm na deficience vznikl\u00E9 v souvislosti s infek\u010Dn\u00EDmi chorobami, u ps\u016F i na studium autoimunitn\u00EDch a alergick\u00FDch chorob. Tato sledov\u00E1n\u00ED budou kombinov\u00E1na prohlouben\u00FDm studiem patogeneze vybran\u00FDch infek\u010Dn\u00EDch chorob z hledisk a jejich ovlivn\u011Bn\u00ED imunitn\u00EDho syst\u00E9mu; u skotu zejm\u00E9na slizni\u010Dn\u00ED choroby (BVD-MD). P\u0159edpokl\u00E1dan\u00E9 v\u00FDstupy budou m\u00EDt p\u0159edev\u0161\u00EDm charakter odborn\u00FDch sd\u011Blen\u00ED a expertn\u00EDch zpr\u00E1v pro pot\u0159eby St\u00E1tn\u00ED veterin\u00E1rn\u00ED spr\u00E1vy \u010CR, praktick\u00FDch l\u00E9ka\u0159\u016F, chovatel\u016F a dal\u0161\u00ED"@cs . "1"^^ . "Disorders of the animal immune system: their relation to infectious diseases and role in morbidity and health protection."@en . "7"^^ . . "0"^^ . . "3778"^^ . "7"^^ . . . . . "0"^^ . . "3778"^^ . . . "Choroby imunitn\u00EDho syst\u00E9mu zv\u00ED\u0159at: jejich vztah k infek\u010Dn\u00EDm nemocem a vliv na celkovou odolnost a poruchy zdravotn\u00EDho stavu sou\u010Dasn\u00FDch populac\u00ED."@cs . .