"prostate cancer; uroinfection; inflammation; Papillomavirus; herpetic virus; Chlamydia trachomatis; Ureaplasma; Mycoplasma"@en . . "6"^^ . "2"^^ . "Soubor bude tvo\u0159en pacienty s biopticky ov\u011B\u0159en\u00FDm karcinomem prostaty z histopatologick\u00E9ho prepar\u00E1tu z\u00EDskan\u00E9ho p\u0159i retropubick\u00E9 radik\u00E1ln\u00ED prostatektomii nebo benign\u00ED hyperplazie z prepar\u00E1tu z\u00EDskan\u00E9ho suprapubickou transvezik\u00E1ln\u00ED prostatektomi\u00ED. Z odb\u011Bru perifern\u00ED krve vy\u0161et\u0159\u00EDme p\u0159\u00EDtomnost s\u00E9rov\u00FDch protil\u00E1tek proti sledovan\u00FDm patogen\u016Fm. U s\u00E9ropozitivn\u00EDch pacient\u016F provedeme vy\u0161et\u0159en\u00ED tk\u00E1n\u011B prostaty na pr\u016Fkaz sledovan\u00FDch patogen\u016F pomoc\u00ED molekul\u00E1rn\u011B-genetick\u00FDch metod. Vyhodnot\u00EDme vztah sledovan\u00FDch infek\u010Dn\u00EDch uropatogen\u016F k biologick\u00E9mu chov\u00E1n\u00ED n\u00E1doru a kontroln\u00ED skupin\u011B. Projekt je zam\u011B\u0159en na aktu\u00E1ln\u00ED onkologickou problematiku, p\u0159edpokl\u00E1d\u00E1me vyu\u017Eit\u00ED v\u00FDsledk\u016F pro dal\u0161\u00ED aplikovan\u00FD v\u00FDzkum p\u0159i dlouhodob\u00E9m sledov\u00E1n\u00ED pacient\u016F, screeningu karcinomu prostaty a racionalizaci diagnosticko-l\u00E9\u010Debn\u00FDch postup\u016F."@cs . . "4455"^^ . "V\u00FDznam infekce prostaty v etiopatogenezi karcinomu prostaty"@cs . . "2011-12-31+01:00"^^ . "The population will consist of subjects with PC (histologically verified) from retropubic radical prostatectomy or benign prostatic hyperplasia from tissue from suprapubic transvesical prostatectomy. In serum positive patients will be performed examination of the tissue specimens and their collection for the purpose of molecular genetic testing. The project focuses on actual oncology issues. We expect the results to be used in applied research, long-time patient dispensarization, PC screening and improving diagnostic and therapeutic approaches"@en . . . . . "2009-01-01+01:00"^^ . "0"^^ . "1"^^ . . "4455"^^ . . "6"^^ . "The role of chronic infection in etiopathogenesis of prostate carcinoma"@en . . . .