. . "2709"^^ . . "Protil\u00E1tky proti HLA antigen\u016Fm po transplantaci ledviny a jejich vztah k chronick\u00E9 rejekci"@cs . . "2788"^^ . "The clinical significance of antibodies against HLA antigens (alloantibodies) in patients after kidney transplantation and its relation to chronic rejection is not still completely elucidated. The aim of this study is to investigate the correlation between antibodies to HLA antigens after transplantation and the morphological and clinical symptoms of chronic rejection. Alloantibodies will be analyzed according to their HLA (or non-HLA) specificity, immunoglobulin class and dynamics of development."@en . . "4"^^ . "0"^^ . . "kidney transplantation; chronic rejection; antibodies; HLA; ELISA; flow cytometry"@en . "4"^^ . "Klinick\u00FD v\u00FDznam vzniku protil\u00E1tek proti HLA antigen\u016Fm (aloprotil\u00E1tek) u pacient\u016F po transplantaci ledviny a jejich vztah k chronick\u00E9 rejekci nen\u00ED zat\u00EDm dostate\u010Dn\u011B vyjasn\u011Bn. V navrhovan\u00E9m projektu si klademe za c\u00EDl studovat korelaci mezi vznikem protil\u00E1tek proti HLA antigen\u016Fm po transplantaci a morfologick\u00FDmi a klinick\u00FDmi p\u0159\u00EDznaky chronick\u00E9 rejekce. Protil\u00E1tky budou analyzov\u00E1ny podle jejich specificity proti HLA antigen\u016Fm, dynamiky vzniku a imunoglobulinov\u00E9 t\u0159\u00EDdy."@cs . "Antibodies to HLA antigens and their relevance for the develpoment of chronic rejection after kidney transplantation"@en . . "0"^^ . . . "1"^^ . .