"2011-12-31+01:00"^^ . "Fosfolipidov\u00FD sign\u00E1ln\u00ED syst\u00E9m je mechanismus, kter\u00FDm rostlinn\u00E9 i \u017Eivo\u010Di\u0161n\u00E9 bu\u0148ky reaguj\u00ED na sign\u00E1ly stresov\u00E9 povahy p\u0159ich\u00E1zej\u00EDc\u00ED z vn\u011Bj\u0161\u00EDho prost\u0159ed\u00ED. Fosfolipasa A2, D a fosfatidylinositol - specifick\u00E1 fosfolipasa C jsou kl\u00ED\u010Dov\u00E9 enzymy tohoto sign\u00E1ln\u00EDho mechanismu. Tyto enzymy tvo\u0159\u00ED vysoce organizovanou s\u00ED\u0165, kter\u00E1 je schopna specificky reagovat na rozli\u010Dn\u00E9 extracelul\u00E1rn\u00ED podn\u011Bty. V\u00A0minul\u00E9m roce byla pops\u00E1na u rostlin dal\u0161\u00ED fosfolipasa C - enzym specificky hydrolyzuj\u00EDc\u00ED fosfatidylcholin. N\u00E1mi publikovan\u00E1 data a na\u0161e dal\u0161\u00ED p\u0159edb\u011B\u017En\u00E9 v\u00FDsledky nazna\u010Duj\u00ED, \u017Ee se tento enzym pod\u00EDl\u00ED t\u00E9\u017E na p\u0159enosu stresov\u00FDch sign\u00E1l\u016F. Jeho \u00FA\u010Dast v\u00A0metabolismu lipid\u016F je nicm\u00E9n\u011B tak\u00E9 mo\u017En\u00E1.C\u00EDlem p\u0159edkl\u00E1dan\u00E9ho projektu je objasn\u011Bn\u00ED role fosfastidylcholin - specifick\u00E9 fosfolipasy C v\u00A0rostlin\u00E1ch b\u011Bhem biotick\u00E9ho respektive abiotick\u00E9ho stresu a to na \u00FArovni biochemick\u00E9, molekul\u00E1rn\u011B biologick\u00E9 i funk\u010Dn\u00ED. Z\u00E1kladn\u00ED modelovou rostlinou bude husen\u00ED\u010Dek Thall\u016Fv. V\u00FDsledky budou ov\u011B\u0159eny (a jejich obecn\u00E1 platnost potvrzena) na jedn\u00E9 z\u00A0celosv\u011Btov\u011B nejd\u016Fle\u017Eit\u011Bj\u0161\u00EDch plodin - kuku\u0159ici"@cs . "1"^^ . . . . . . . "Phosphatidylcholine-specific phospholipase C at the crossing point of stress signalling pathways"@en . . . "5745"^^ . "abiotick\u00FD stres; biotick\u00FD stres; fosfolipasa C; p\u0159enost sign\u00E1l\u016F"@en . "0"^^ . "5745"^^ . "3"^^ . . . "Phospholipide signalling in both, plant and animal cells is one of the well accepted mechanisms of stress signal transduction. Key enzymes of this signalling pathway are phospholipase A2, D and phosphoinositide-specific phospholipase C. These enzymes are organised into complex network, which is then able to react specifically to different extracellular stimuli. Since last year there are evidences that another phospholipase C - phosphatidylcholine - specific (PC-PLC) - exists in plants. Our published and additional preliminary results suggest activation of this enzyme during response of plants to stress signals. However participating of this enzyme in general lipid metabolism is also conceivable.The objective of this proposal is disclosure of the role of PC-PLC on biochemical, molecular and functional levels in plants particularly with respect to abiotic and biotic stresses. As theoretical model Arabidopsis thaliana will be used and results will be compared (and confirmed) using one of the worldwide most important crop - maize."@en . "0"^^ . "3"^^ . "2007-01-01+01:00"^^ . "Fosfatidylcholin - specifick\u00E1 fosfolipasa C v pr\u016Fse\u010D\u00EDku stresov\u00FDch sign\u00E1ln\u00EDch drah"@cs . . .