. "0"^^ . "Alkaloid z m\u00E1ku, thebain, slou\u017E\u00ED jako v\u00FDchoz\u00ED surovina pro v\u00FDrobu r\u016Fzn\u00FDch l\u00E9\u010Div v\u010Detn\u011B nen\u00E1vykov\u00FDch analgetik. M\u00E1k listenat\u00FD (Papaver bracteatum) nelze pou\u017E\u00EDt pro produkci thebainu v na\u0161ich podm\u00EDnk\u00E1ch, proto\u017Ee jeho p\u011Bstov\u00E1n\u00ED je neekonomick\u00E9. U druhu Papaver somniferum tvo\u0159\u00ED thebain mezistupe\u0148 na cest\u011B synt\u00E9zy morfinu, je proto velmi pravd\u011Bpodobn\u00E9, \u017Ee existuje takov\u00FD mutant, u kter\u00E9ho je p\u0159em\u011Bna thebainu na morfin inhibov\u00E1na.. C\u00EDlem projektu je vypracovat vhodnou screeningovou metodu detekce obsahu thebainu a nal\u00E9zt v\u00FDchoz\u00ED materi\u00E1l se zv\u00FD\u0161en\u00FDm obsahem thebainu pro n\u00E1sledn\u00E9 v\u00FDzkumn\u00E9 a \u0161lechtitelsk\u00E9 vyu\u017Eit\u00ED."@cs . . "1"^^ . "1"^^ . . "0"^^ . . "1271"^^ . "The development of the screening method and the searching of poppy (Papaver somniferum) gene ressources with high thebaine content"@en . . "1"^^ . "1271"^^ . . . . . "The poppy alkaloid thebain serve as the source of the initial material for the production of medicaments incl. analgetics. The poppy Papaver bracteatum is not suitable for thebain production in our climatically conditions, because the growing of this poppy is uneconomically. At the species Papaver somniferum the thebain constitute an interline in the morphine syntheses line, therefore it is highly probable that the mutant will exist with the inhibition of thebain conversion to the morphine. The aim othis project is to elaborate the suitable screening method for the detection of thebain content and to find the source material with higher thebain content for the follow up research and breeding purposes."@en . . . "V\u00FDvoj screeningov\u00E9 metody a vyhled\u00E1v\u00E1n\u00ED genov\u00FDch zdroj\u016F m\u00E1ku set\u00E9ho (Papaver somniferum) s vysok\u00FDm obsahem thebainu"@cs .