"40"^^ . "The proposed project deals with design of a high-resolution optical-electrical recording system and its use in analysis of T-wave alternans (TWA) in electrocardiographic signals. First part of the system is based on a possibility to record electrical signals from living subject via measurement of changes in optical properties of the tissue. The second part consists of a high-resolution electrocardiograph using touch-less electrodes. The developed system will significantly contribute to the quality ofrecorded signals and allow to develop new reliable methods for cardiac arrhythmia analysis. The specific aims of the project are: to build a high-resolution fluorescent optical recording system using low-noise light detectors and a fast high-precision A/D converter, to build a high-resolution electrode recording system with orthogonal leads and based on a three-channel high-precision A/D converter, to experimentally verify the recording systems on isolated hearts perfused according to Langendorff, to"@en . "2889"^^ . . "1"^^ . . . . "0"^^ . . "High resolution optical recording of action potentials for analysis of T-wave alternans"@en . . "Optick\u00E9 sn\u00EDm\u00E1n\u00ED ak\u010Dn\u00EDch potenci\u00E1l\u016F s vysok\u00FDm rozli\u0161en\u00EDm pro anal\u00FDzu alternac\u00ED T-vlny EKG sign\u00E1lu"@cs . . . "1"^^ . "Neuvedeno."@en . . . . . "40"^^ . "Projekt se zab\u00FDv\u00E1 n\u00E1vrhem a realizac\u00ED opticko-elektrick\u00FDm z\u00E1znamov\u00FDm syst\u00E9mem s vysok\u00FDm rozli\u0161en\u00EDm a jeho pou\u017Eit\u00EDm v anal\u00FDze alternanc\u00ED T-vlny (TWA) v elektrokardiografick\u00FDch sign\u00E1lech. Prvn\u00ED \u010D\u00E1st syst\u00E9mu je zalo\u017Eena na mo\u017Enosti zaznamenat elektrick\u00E9 sign\u00E1ly z \u017Eiv\u00E9ho organismu prost\u0159ednictv\u00EDm m\u011B\u0159en\u00ED zm\u011Bn optick\u00FDch vlastnost\u00ED tk\u00E1n\u011B. Druh\u00E1 \u010D\u00E1st syst\u00E9mu je slo\u017Eena z elektrokardiografu s vysok\u00FDm rozli\u0161en\u00EDm a elektrod pro bezdotykov\u00E9 m\u011B\u0159en\u00ED. Vyvinut\u00FD syst\u00E9m v\u00FDrazn\u011B zv\u00FD\u0161\u00ED kvalitu zaznamen\u00E1van\u00FDch sign\u00E1l\u016F a umo\u017En\u00ED v\u00FDvoj nov\u00FDch spolehliv\u00FDch metod anal\u00FDzy srde\u010Dn\u00EDch arytmi\u00ED. Konkr\u00E9tn\u00ED c\u00EDle projektu jsou tyto: v\u00FDvoj fluorescentn\u00EDho optick\u00E9ho z\u00E1znamov\u00E9ho za\u0159\u00EDzen\u00ED s vysok\u00FDm rozli\u0161en\u00EDm vyu\u017E\u00EDvaj\u00EDc\u00EDho n\u00EDzko\u0161umov\u00FDch fotodetektor\u016F a rychl\u00E9ho p\u0159esn\u00E9ho A/D p\u0159evodn\u00EDku, v\u00FDvoj elektrodov\u00E9ho z\u00E1znamov\u00E9ho za\u0159\u00EDzen\u00ED s vysok\u00FDm rozli\u0161en\u00EDm s ortogon\u00E1ln\u00EDmi svody a t\u0159\u00EDkan\u00E1lov\u00FDm p\u0159esn\u00FDm p\u0159evodn\u00EDkem, experiment\u00E1ln\u00ED ov\u011B\u0159en\u00ED z\u00E1znamov\u00FDch za\u0159\u00EDzen\u00ED v experimentech na izolovan\u00E9m srdci podle Langendorffa, experiment\u00E1ln\u00ED nalezen\u00ED spojen\u00ED"@cs . "2889"^^ .