. . . "Nov\u011B vypracovan\u00E9 metody m\u011B\u0159en\u00ED konstant spin-spinov\u00E9 interakce mezi j\u00E1dry 29Si a 13C v roztoc\u00EDch vyu\u017Eij\u00ED p\u0159\u00EDstrojov\u00FDch mo\u017Enost\u00ED trojn\u00E9 rezonance jader 1H-13C-29Si, kter\u00E9 podstatn\u00FDm zp\u016Fsobem zvy\u0161uj\u00ED citlivost m\u011B\u0159en\u00ED a dovoluj\u00ED se vyhnout n\u00E1kladn\u00E9mu izotopick\u00E9mu obohacov\u00E1n\u00ED b\u011B\u017En\u00E9mu v bio-NMR. T\u011Bmito metodami budou zm\u011B\u0159eny modelov\u00E9 \u0159ady, kter\u00E9 poskytnou z\u00E1vislosti gemin\u00E1ln\u00EDch konstant (nap\u0159. konstant ve fragmentu 29Si-O-13C) a vicin\u00E1ln\u00EDch konstant tohoto typu na vazebn\u00FDch a dihedr\u00E1ln\u00EDch \u00FAhlech (analog Karplusovy rovnice) a posl\u00E9ze i vliv substituent\u016F (analog Altona-Haasnotov\u00FDch rovnic). Tyto, pro k\u0159em\u00EDk dosud nepopsan\u00E9 z\u00E1vislosti umo\u017En\u00ED ur\u010Dit spolu s dal\u0161\u00EDmi m\u011B\u0159en\u00EDmi (zejm\u00E9na Nukle\u00E1rn\u00EDho Overhauserova Efektu) detailn\u00ED strukturu silyl skupin v organok\u0159emi\u010Dit\u00FDch slou\u010Denin\u00E1ch a kopolym\u00E9rech a to v\u010Detn\u011B jejich konformac\u00ED. Z\u00EDskan\u00E9 \u00FAdaje, kter\u00E9 dosud zcela chyb\u00ED, jsou kl\u00ED\u010Dov\u00E9 pro vyvoj nov\u00FDch organok\u0159emi\u010Dit\u00FDch l\u00E1tek s po\u017Eadovan\u00FDmi vlastnostmi zejm\u00E9na pro nanotechnologie."@cs . . "Structure of silyl moieties through J(29Si-13C) couplings as determined by triple {1H, 13C}29Si NMR experiments"@en . . "2011-12-31+01:00"^^ . "3633"^^ . "Struktura skupin obsahuj\u00EDc\u00EDch k\u0159em\u00EDk a J(29Si-13C) interakce m\u011B\u0159en\u00E9 trojnou{1H, 13C}29Si NMR"@cs . "0"^^ . . "0"^^ . . . . "2007-01-01+01:00"^^ . "26"^^ . "NMR; spin-spin coupling; triple resonance; silyl group; molecular structure"@en . "New methods for measurement of spin-spin couplings between 29Si and 13C nuclei in solutions utilize instrumental possibilities of triple resonance of 1H-13C-29Si nuclei which enhance the sensitivity to the extent that expensive isotopic enrichment, common for bio-NMR, is not needed. Using these experiments model series of compounds will be measured to produce the Karplus-type dependence of the vicinal 29Si-13C couplings on dihedral angles and, subsequently, also the dependence on the nature of substituents (analogous to Altona-Haasenot equations). These dependences allow, together with other measurements (notably of Nuclear Overhauser Effects), studies of the structure and conformation of silyl groups in solutions of organosilicon compounds and copolymers. The data, so far entirely missing for silicon, are of key importance for design of new compounds with required properties as needed by nanotechnology."@en . "3633"^^ . . "26"^^ . "1"^^ . .