<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A role used to specify that an enzyme is directly responsible for metabolizing a chemical or drug into an active form, inactive form, or both. The domain and range for this role are 'Drug, Food, Chemical or Biomedical Material' and 'Gene Product', respectively.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>