<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A role used to relate a disease to the general site, structure or system where the specific pathological process is located. The domain and the range for this role are 'Disease, Disorder or Finding' and 'Anatomic Structure, System, or Substance', respectively.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:P98
The role, Disease_Has_Associated_Anatomic_Site, is more general than the role, Disease_Has_Primary_Anatomic_Site. Furthermore, when viewed with the role, Disease_Has_Metastatic_Anatomic_Site, there emerges a role hierarchy, where one role specializes the meaning of another, more general role. Roles relating disease to anatomy start with a general assertion of association, often at very high level (e.g. Skin Disorder and Skin), and then add more specific primary/metastatic associations where appropriate for more specific concepts.