<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-source>NCI</n0:def-source><n0:def-definition>Any agent that helps restore the function of the endogenous mutated protein. Pharmaceutical chaperones may help stabilize the protein structure thereby restoring folding and/or preventing misfolding of the protein. This may prevent degradation or inactivation of the protein.</n0:def-definition></n0:ComplexDefinition>