Anal cancer; Bladder cancer; Breast cancer; Bronchogenic cancer; Cervical cancer; Colorectal cancer; Esophageal cancer; Gastric carcinoma; Head and neck cancer; Liver cancer; Pancreatic carcinoma; Pterygia
nci:P303
Anal cancer; Bladder cancer; Breast cancer; Liver cancer; Liver metastases; Mesothelioma; Non-small cell lung cancer
nci:P325
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>An anticancer drug that belongs to the family of drugs called antitumor antibiotics.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and dione moieties. Bioreductively activated mitomycin antibiotics generate oxygen radicals and alkylate DNA, forming inter-strand cross-links and inhibiting DNA synthesis.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>