<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A formula which takes into account the physiologic shortening of the QT interval which occurs as the heart rate increases, permitting comparison of the QT interval across a range of rates. The linear correction formula uses population-based data obtained and validated using a large cohort of subjects. This method theoretically corrects the QT interval to that which would be observed at a heart rate of 1 cycle per second. (NCI)</n0:def-definition><n0:def-source>CDISC</n0:def-source></n0:ComplexDefinition>
nci:P366
QTcLC-Linear_Correction_Formula
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>QTcLC - Linear Correction Formula</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm><n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Linear Correction Formula</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm><n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>QTcLC - Linear Correction Formula</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>CDISC</n0:term-source><n0:source-code>SDTM-EGTEST</n0:source-code></n0:ComplexTerm><n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>QTcLC - Linear Correction Formula</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>CDISC</n0:term-source></n0:ComplexTerm><n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>QTcLC - Linear Correction Formula</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm><n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>QTCLC</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>CDISC</n0:term-source><n0:source-code>SDTM-EGTESTCD</n0:source-code></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A formula which takes into account the physiologic shortening of the QT interval which occurs as the heart rate increases, permitting comparison of the QT interval across a range of rates. The linear correction formula uses population-based data obtained and validated using a large cohort of subjects. Using this method, the corrected QT interval is independent of the ventricular rate.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>