HTML Microdata document

This HTML5 document contains 39 embedded RDF statements represented using HTML+Microdata notation.

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Namespace Prefixes

Prefix	IRI
rdfs	http://www.w3.org/2000/01/rdf-schema#
rdf	http://www.w3.org/1999/02/22-rdf-syntax-ns#
owl	http://www.w3.org/2002/07/owl#
nci	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdh	http://www.w3.org/2001/XMLSchema#

Statements

Subject Item: nci:C46050
rdf:type: owl:Class
rdfs:label: CYP2D6*18 Allele
rdfs:subClassOf: nci:C26517 _:vb656014 _:vb656015 _:vb656016 _:vb656017 _:vb656018
nci:P100: 124030
nci:P102: NM_000106
nci:P106: Gene or Genome
nci:P108: CYP2D6*18 Allele
nci:P171: 8946471
nci:P207: C1707214
nci:P366: CYP2D6_18_Allele
nci:P90: <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*18 Allele</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2D6*18</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2D6*18 Allele</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2D6(J9)</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2D6, g.4125insGTGCCCACT</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P96: Cytochrome P450 2D6
nci:P97: <n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>Human CYP2D6*18 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*18 protein. The CYP2D6*18 allele exhibits a nine nucleotide insertion (g.4125insGTGCCCACT) in exon 9. This alteration increased the Km value of the cytochrome P450 2D6*18 protein toward bufuralol, resulting in decreased enzymatic activity.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:P98: Ethnicity Association: Asian
nci:code: C46050

Subject Item: _:vb656014
rdf:type: owl:Restriction
owl:onProperty: nci:R158
owl:someValuesFrom: nci:C26633

Subject Item: _:vb656015
rdf:type: owl:Restriction
owl:onProperty: nci:R153
owl:someValuesFrom: nci:C19295

Subject Item: _:vb656016
rdf:type: owl:Restriction
owl:onProperty: nci:R158
owl:someValuesFrom: nci:C26533

Subject Item: _:vb656017
rdf:type: owl:Restriction
owl:onProperty: nci:R159
owl:someValuesFrom: nci:C45423

Subject Item: _:vb656018
rdf:type: owl:Restriction
owl:onProperty: nci:R155
owl:someValuesFrom: nci:C13766