SPARQL | HTML Microdata document
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Namespace Prefixes
Prefix IRI
rdfs http://www.w3.org/2000/01/rdf-schema#
rdf http://www.w3.org/1999/02/22-rdf-syntax-ns#
owl http://www.w3.org/2002/07/owl#
nci http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdh http://www.w3.org/2001/XMLSchema#
Statements
Subject Item nci:C46015
rdf:type
owl:Class
rdfs:label
CYP2C9*8 Allele
rdfs:subClassOf
_:vb655945
_:vb655946
_:vb655947
_:vb655948
_:vb655949
_:vb655950
nci:C21597
nci:P100
601130
nci:P102
NM_000771
nci:P106
Gene or Genome
nci:P108
CYP2C9*8 Allele
nci:P171
15284535
nci:P207
C1707206
nci:P315
rs7900194
nci:P366
CYP2C9_8_Allele
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2C9, R150H</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2C9, c.449G>A</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2C9*8</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*8 Allele</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CYP2C9*8 Allele</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P96
Cytochrome P450 2C8
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>Human CYP2C9*8 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*8 protein. The CYP2C9*8 allele exhibits a clinically-relevant SNP (c.449G>A) in exon 3 that results in a R150H coding change. This alteration in protein sequence increases the enzymatic activity of the cytochrome P450 2C9*8 protein.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:P98
Ethnicity Association: African American; Black African
nci:code
C46015
Subject Item _:vb655945
rdf:type
owl:Restriction
owl:onProperty
nci:R155
owl:someValuesFrom
nci:C13596
Subject Item _:vb655946
rdf:type
owl:Restriction
owl:onProperty
nci:R158
owl:someValuesFrom
nci:C26533
Subject Item _:vb655947
rdf:type
owl:Restriction
owl:onProperty
nci:R153
owl:someValuesFrom
nci:C18134
Subject Item _:vb655948
rdf:type
owl:Restriction
owl:onProperty
nci:R159
owl:someValuesFrom
nci:C45421
Subject Item _:vb655949
rdf:type
owl:Restriction
owl:onProperty
nci:R153
owl:someValuesFrom
nci:C45641
Subject Item _:vb655950
rdf:type
owl:Restriction
owl:onProperty
nci:R158
owl:someValuesFrom
nci:C26633