<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>Growth Factor Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction and often spatial complementarity with extracellular signaling molecules (ligands) involved in the control of target cell proliferation, survival, and differentiation.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>