<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>An exaggerated response by the immune system to a drug or other substance.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition><n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A disorder characterized by an adverse local or general response from exposure to an allergen.</n0:def-definition><n0:def-source>CTCAE</n0:def-source></n0:ComplexDefinition><n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>Hypersensitivity; a local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized.</n0:def-definition><n0:def-source>FDA</n0:def-source></n0:ComplexDefinition><n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized.</n0:def-definition><n0:def-source>CDISC</n0:def-source></n0:ComplexDefinition>
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A local or general reaction of an organism following contact with a specific allergen to which it has been previously exposed and to which it has become sensitized.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>