SPARQL | HTML Microdata document
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Namespace Prefixes
Prefix IRI
n5 http://linked.opendata.cz/resource/mesh/concept/
rdfs http://www.w3.org/2000/01/rdf-schema#
rdf http://www.w3.org/1999/02/22-rdf-syntax-ns#
owl http://www.w3.org/2002/07/owl#
n4 http://linked.opendata.cz/ontology/mesh/
nci http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
n7 http://linked.opendata.cz/resource/ndfrt/ingredient/
xsdh http://www.w3.org/2001/XMLSchema#
Statements
Subject Item nci:C293
rdf:type
owl:Class
rdfs:label
Azlocillin
rdfs:subClassOf
nci:C1500
nci:A5
nci:C65243
nci:A8
nci:C63923
nci:P106
Antibiotic
Organic Chemical
nci:P108
Azlocillin
nci:P207
C0004499
nci:P210
37091-66-0
nci:P319
HUM6H389W0
nci:P322
FDA
nci:P325
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A semisynthetic ampicillin-derived acylureido penicillin.</n0:def-definition><n0:def-source>MSH2002_06_01</n0:def-source></n0:ComplexDefinition>
nci:P329
39160
nci:P330
39160
nci:P350
C20H23N5O6S
nci:P366
Azlocillin
nci:P368
CHEBI:2956
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>AZLOCILLIN</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>HUM6H389W0</n0:source-code></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Azlin</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Azlocillin</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A semisynthetic, extended spectrum acylampicillin with antibacterial activity. Azlocillin binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linking of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code
C293
owl:sameAs
n7:N0000005863
n4:hasConcept
n5:M0002078