<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A class of vaccines with potential antineoplastic activity. Peripheral blood lymphocytes (PBL) are first harvested from a cancer patient and induced to express a particular tumor-associated antigen or multiple antigens. Autologous vaccination with activated PBL may stimulate the host immune system to produce antibodies and/or mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the antigen(s), resulting in decreased tumor growth. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>