SPARQL | HTML Microdata document
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Namespace Prefixes
Prefix IRI
n6 http://linked.opendata.cz/resource/mesh/concept/
rdfs http://www.w3.org/2000/01/rdf-schema#
rdf http://www.w3.org/1999/02/22-rdf-syntax-ns#
n5 http://linked.opendata.cz/ontology/mesh/
owl http://www.w3.org/2002/07/owl#
nci http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdh http://www.w3.org/2001/XMLSchema#
Statements
Subject Item nci:C2471
rdf:type
owl:Class
rdfs:label
Ad5CMV-p53 Gene
rdfs:subClassOf
_:vb644280
_:vb644281
_:vb644277
_:vb644278
_:vb644279
nci:C49146
nci:P106
Pharmacologic Substance
Virus
nci:P108
Ad5CMV-p53 Gene
nci:P175
683550
nci:P207
C1135129
nci:P303
Head and Neck cancer; Lip and oral cavity cancer; Oropharyngeal cancer
nci:P329
43016
nci:P330
43016
nci:P366
Ad5CMV-p53_Gene
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Adenovirus p53</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>INGN-201</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Advexin</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Ad-p53</n0:term-name><n0:term-group>AB</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Ad5CMV-p53 Gene</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Ad5CMV p53 Gene</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>p53 Gene, Ad5CMV</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Adeno-p53</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>RPR/INGN-201</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A replication-defective adenoviral-CMV vector that encodes a wild-type p53 gene. Ad5CMV-p53 induces tumor cells that have been transfected with the vector to produce wild-type p53, a tumor suppressor gene that is deleted or mutated in a significant number of cancers. In transfected tumor cells, the wild-type p-53 gene product exerts an antitumor effect by blocking cell cycle progression at the G1/S regulation point, activating DNA repair proteins in the presence of DNA damage, and initiating apoptosis when DNA damage is irreparable. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code
C2471
n5:hasConcept
n6:M0501270
Subject Item _:vb644277
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C16513
Subject Item _:vb644278
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C17554
Subject Item _:vb644279
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C21230
Subject Item _:vb644280
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C20150
Subject Item _:vb644281
rdf:type
owl:Restriction
owl:onProperty
nci:R124
owl:someValuesFrom
nci:C21050