Aggressive B-cell Lymphoma; Previously Treated Diffuse Large Cell Lymphoma; Intermediate or High Grade Recurrent or Refractory B-cell Non-Hodgkins Lymphoma.
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A radioimmunoconjugate of a murine monoclonal antibody, MoAb Lym-1, labeled with iodine 131 (I-131). MoAb Lym-1 recognizes an epitope of the histocompatibility antigen HLA-DR, which is over-expressed on most B-cell lymphomas. I-131 MoAb Lym-1 delivers beta and gamma radiation emitting I-131 nuclide directly to tumor cells that express HLA-DR, thereby allowing imaging and/or treatment of cancers.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>